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Obesity and Coronary Artery Disease: An Updated Systematic Review 2022
The primary goal is to identify the pathogenesis of cardiovascular illnesses in obese patients. Articles were extracted using the MeSH search approach from PubMed and Google Scholar databases. Inclusion and exclusion criteria were used, and duplicates were eliminated. Eight publications were finally...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588166/ https://www.ncbi.nlm.nih.gov/pubmed/36299943 http://dx.doi.org/10.7759/cureus.29480 |
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author | Manoharan, Mohana Priya Raja, Rabab Jamil, Aneeque Csendes, Denise Gutlapalli, Sai Dheeraj Prakash, Keerthana Swarnakari, Kiran Maee Bai, Meena Desai, Darshi M Desai, Aditya Penumetcha, Sai Sri |
author_facet | Manoharan, Mohana Priya Raja, Rabab Jamil, Aneeque Csendes, Denise Gutlapalli, Sai Dheeraj Prakash, Keerthana Swarnakari, Kiran Maee Bai, Meena Desai, Darshi M Desai, Aditya Penumetcha, Sai Sri |
author_sort | Manoharan, Mohana Priya |
collection | PubMed |
description | The primary goal is to identify the pathogenesis of cardiovascular illnesses in obese patients. Articles were extracted using the MeSH search approach from PubMed and Google Scholar databases. Inclusion and exclusion criteria were used, and duplicates were eliminated. Eight publications were finally included in this research study after two authors independently completed the quality check appraisal. Seven observational studies and one narrative review were found in our search. The publications evaluated the risk of coronary artery disease in metabolically healthy obese people with that of unhealthy obese adults and evaluated the effects of adipose tissue-mediated inflammation. Additionally, they offered several explanations for the obesity problem. Studies have indicated that adipocytokines and their pro-inflammatory cytokines have significantly affected the development of cardiovascular disease in obese subjects. The relationship between metabolically unhealthy people with increased risk for coronary artery disease (CAD) is unclear. It has also been shown that metabolically healthy obese persons are still at risk for developing coronary artery disease (CAD), as explained in certain studies in which inflammation plays a vital role in obese people. There hasn't been much data on the advantages of being physically active in overweight people, but obese people have to change their lifestyle as a first measure. |
format | Online Article Text |
id | pubmed-9588166 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-95881662022-10-25 Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 Manoharan, Mohana Priya Raja, Rabab Jamil, Aneeque Csendes, Denise Gutlapalli, Sai Dheeraj Prakash, Keerthana Swarnakari, Kiran Maee Bai, Meena Desai, Darshi M Desai, Aditya Penumetcha, Sai Sri Cureus Cardiology The primary goal is to identify the pathogenesis of cardiovascular illnesses in obese patients. Articles were extracted using the MeSH search approach from PubMed and Google Scholar databases. Inclusion and exclusion criteria were used, and duplicates were eliminated. Eight publications were finally included in this research study after two authors independently completed the quality check appraisal. Seven observational studies and one narrative review were found in our search. The publications evaluated the risk of coronary artery disease in metabolically healthy obese people with that of unhealthy obese adults and evaluated the effects of adipose tissue-mediated inflammation. Additionally, they offered several explanations for the obesity problem. Studies have indicated that adipocytokines and their pro-inflammatory cytokines have significantly affected the development of cardiovascular disease in obese subjects. The relationship between metabolically unhealthy people with increased risk for coronary artery disease (CAD) is unclear. It has also been shown that metabolically healthy obese persons are still at risk for developing coronary artery disease (CAD), as explained in certain studies in which inflammation plays a vital role in obese people. There hasn't been much data on the advantages of being physically active in overweight people, but obese people have to change their lifestyle as a first measure. Cureus 2022-09-23 /pmc/articles/PMC9588166/ /pubmed/36299943 http://dx.doi.org/10.7759/cureus.29480 Text en Copyright © 2022, Manoharan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Manoharan, Mohana Priya Raja, Rabab Jamil, Aneeque Csendes, Denise Gutlapalli, Sai Dheeraj Prakash, Keerthana Swarnakari, Kiran Maee Bai, Meena Desai, Darshi M Desai, Aditya Penumetcha, Sai Sri Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 |
title | Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 |
title_full | Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 |
title_fullStr | Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 |
title_full_unstemmed | Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 |
title_short | Obesity and Coronary Artery Disease: An Updated Systematic Review 2022 |
title_sort | obesity and coronary artery disease: an updated systematic review 2022 |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588166/ https://www.ncbi.nlm.nih.gov/pubmed/36299943 http://dx.doi.org/10.7759/cureus.29480 |
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