Cargando…
A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm
BACKGROUND: Intracranial aneurysm serves as a prevalent cerebral disorder leading to the low-quality life and financial burden of the patients. Flow diversion and coil embolization have been confirmed as common therapeutic strategies for intracranial aneurysms. In this work, we identified and compar...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588347/ https://www.ncbi.nlm.nih.gov/pubmed/36284988 http://dx.doi.org/10.1155/2022/2925366 |
_version_ | 1784814112074629120 |
---|---|
author | Jin, Ji Wu, Yongqiang Yang, Biao Ren, Yeqing Sun, Yanqi He, Jianhang Wang, Xiaogang Guo, Geng |
author_facet | Jin, Ji Wu, Yongqiang Yang, Biao Ren, Yeqing Sun, Yanqi He, Jianhang Wang, Xiaogang Guo, Geng |
author_sort | Jin, Ji |
collection | PubMed |
description | BACKGROUND: Intracranial aneurysm serves as a prevalent cerebral disorder leading to the low-quality life and financial burden of the patients. Flow diversion and coil embolization have been confirmed as common therapeutic strategies for intracranial aneurysms. In this work, we identified and compared the cost between the flow diversion and coil embolization in the treatment of intracranial aneurysms in a meta-analysis. METHODS: We downloaded literatures that are published before Feb 2021 from Cochrane Library, Embase, and Pubmed using terms including “flow diversion”, “pipeline embolization device”, “coil embolization”, “coiling”, “Intracranial aneurysms”, and “Cerebral aneurysms”. The data were analyzed by STATA 15.1. Differences in treatment costs were determined by WMD (95% CI). RESULTS: A total of 1332 articles were included in the search of the limited terms, and 8 were selected after eliminating duplicate and unwanted studies. Our data indicated that the total cost of flow diversion for intracranial aneurysms is significantly lower than coil embolization (WMD = −4419.12, 95% CI: -6292.21 to -2546.03, p ≤ 0.001). In addition, we explored the retreatment hospitalization cost of flow diversion and coil embolization for intracranial aneurysms. We found that the retreatment hospitalization cost of flow diversion for intracranial aneurysms is significantly higher than coil embolization (WMD = 3203.85, 95% CI: 1904.60 to 4503.10, p ≤ 0.001). CONCLUSION: We concluded that the total cost was lower, and the retreatment hospitalization costs of flow diversion were higher than coil embolization for the treatment of intracranial aneurysms. Our finding provides valuable insights into the application of flow diversion and coil embolization in intracranial aneurysm therapy. Flow diversion may be applied as a major treatment with the consideration of retreatment. |
format | Online Article Text |
id | pubmed-9588347 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-95883472022-10-24 A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm Jin, Ji Wu, Yongqiang Yang, Biao Ren, Yeqing Sun, Yanqi He, Jianhang Wang, Xiaogang Guo, Geng Dis Markers Research Article BACKGROUND: Intracranial aneurysm serves as a prevalent cerebral disorder leading to the low-quality life and financial burden of the patients. Flow diversion and coil embolization have been confirmed as common therapeutic strategies for intracranial aneurysms. In this work, we identified and compared the cost between the flow diversion and coil embolization in the treatment of intracranial aneurysms in a meta-analysis. METHODS: We downloaded literatures that are published before Feb 2021 from Cochrane Library, Embase, and Pubmed using terms including “flow diversion”, “pipeline embolization device”, “coil embolization”, “coiling”, “Intracranial aneurysms”, and “Cerebral aneurysms”. The data were analyzed by STATA 15.1. Differences in treatment costs were determined by WMD (95% CI). RESULTS: A total of 1332 articles were included in the search of the limited terms, and 8 were selected after eliminating duplicate and unwanted studies. Our data indicated that the total cost of flow diversion for intracranial aneurysms is significantly lower than coil embolization (WMD = −4419.12, 95% CI: -6292.21 to -2546.03, p ≤ 0.001). In addition, we explored the retreatment hospitalization cost of flow diversion and coil embolization for intracranial aneurysms. We found that the retreatment hospitalization cost of flow diversion for intracranial aneurysms is significantly higher than coil embolization (WMD = 3203.85, 95% CI: 1904.60 to 4503.10, p ≤ 0.001). CONCLUSION: We concluded that the total cost was lower, and the retreatment hospitalization costs of flow diversion were higher than coil embolization for the treatment of intracranial aneurysms. Our finding provides valuable insights into the application of flow diversion and coil embolization in intracranial aneurysm therapy. Flow diversion may be applied as a major treatment with the consideration of retreatment. Hindawi 2022-10-15 /pmc/articles/PMC9588347/ /pubmed/36284988 http://dx.doi.org/10.1155/2022/2925366 Text en Copyright © 2022 Ji Jin et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Jin, Ji Wu, Yongqiang Yang, Biao Ren, Yeqing Sun, Yanqi He, Jianhang Wang, Xiaogang Guo, Geng A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm |
title | A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm |
title_full | A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm |
title_fullStr | A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm |
title_full_unstemmed | A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm |
title_short | A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm |
title_sort | meta-analysis: cost comparison of flow diversion and coil embolization for intracranial aneurysm |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588347/ https://www.ncbi.nlm.nih.gov/pubmed/36284988 http://dx.doi.org/10.1155/2022/2925366 |
work_keys_str_mv | AT jinji ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT wuyongqiang ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT yangbiao ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT renyeqing ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT sunyanqi ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT hejianhang ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT wangxiaogang ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT guogeng ametaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT jinji metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT wuyongqiang metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT yangbiao metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT renyeqing metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT sunyanqi metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT hejianhang metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT wangxiaogang metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm AT guogeng metaanalysiscostcomparisonofflowdiversionandcoilembolizationforintracranialaneurysm |