Cargando…

Danlou Tablet May Alleviate Vascular Injury Caused by Chronic Intermittent Hypoxia through Regulating FIH-1, HIF-1, and Angptl4

BACKGROUND: Danlou tablet (DLT), the traditional Chinese medicine has been commonly used for dyslipidemia, atherosclerosis, and coronary heart disease. Whether it was effective against vascular injury caused by CIH has remained unknown. The aim of the current study was to observe the effects of DLT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rong, Yi, Wu, Qian, Tang, Jingjing, Liu, Zhiguo, Lv, Qianyu, Ye, Xuejiao, Dong, Yu, Zhang, Yuebo, Li, Guangxi, Wang, Shihan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588356/ https://www.ncbi.nlm.nih.gov/pubmed/36285165 http://dx.doi.org/10.1155/2022/4463108

Ejemplares similares

The Role of Factor Inhibiting HIF (FIH-1) in Inhibiting HIF-1 Transcriptional Activity in Glioblastoma Multiforme
por: Wang, Enfeng, et al.
Publicado: (2014)

Intermittent hypoxia regulates vasoactive molecules and alters insulin-signaling in vascular endothelial cells
por: Sharma, Pragya, et al.
Publicado: (2018)

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
por: Wang, Yihua, et al.
Publicado: (2018)

Factor-inhibiting HIF (FIH) promotes lung cancer progression
por: García-del Río, Ana, et al.
Publicado: (2023)

Hypoxia-inducible miR-182 enhances HIF1α signaling via targeting PHD2 and FIH1 in prostate cancer
por: Li, Yan, et al.
Publicado: (2015)

PPARγ Mediates the Cardioprotective Roles of Danlou Tablet After Acute Myocardial Ischemia-Reperfusion Injury
por: Wei, Meng, et al.
Publicado: (2022)

Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
por: Hyseni, Agon, et al.
Publicado: (2011)

FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α
por: Kang, Jengmin, et al.
Publicado: (2018)

Danlou tablet inhibits high-glucose-induced cardiomyocyte apoptosis via the miR-34a-SIRT1 axis
por: Chen, Rui, et al.
Publicado: (2023)

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity
por: Masson, Norma, et al.
Publicado: (2012)

Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis
por: Khan, M N, et al.
Publicado: (2011)

Efficacy and safety of Danlou tablets in traditional Chinese medicine for coronary heart disease: a systematic review and meta-analysis
por: Mao, WeiLi, et al.
Publicado: (2023)

The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH
por: Melvin, Andrew, et al.
Publicado: (2011)

The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates
por: Hampton-Smith, Rachel J., et al.
Publicado: (2019)

ceRNA regulatory network of FIH inhibitor as a radioprotector for gastrointestinal toxicity by activating the HIF-1 pathway
por: Yang, Yu-wei, et al.
Publicado: (2021)

Traditional Chinese medicine, Danlou tablets alleviate adverse left ventricular remodeling after myocardial infarction: results of a double-blind, randomized, placebo-controlled, pilot study
por: Mao, Shuai, et al.
Publicado: (2016)

Regulation of Transactivation at C-TAD Domain of HIF-1α by Factor-Inhibiting HIF-1α (FIH-1): A Potential Target for Therapeutic Intervention in Cancer
por: Rani, Soniya, et al.
Publicado: (2022)

Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment
por: Feng, Jianbo, et al.
Publicado: (2018)

MicroRNA-122-5p ameliorates tubular injury in diabetic nephropathy via FIH-1/HIF-1α pathway
por: Cheng, Li, et al.
Publicado: (2022)

Overexpression of the HIF Hydroxylases PHD1, PHD2, PHD3 and FIH Are Individually and Collectively Unfavorable Prognosticators for NSCLC Survival
por: Andersen, Sigve, et al.
Publicado: (2011)

Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor
por: Tarhonskaya, Hanna, et al.
Publicado: (2015)

Effects of Danlou tablet for the treatment of stable angina pectoris: A study protocol of a randomized, double-blind, and placebo-controlled clinical trial
por: Yang, Guang, et al.
Publicado: (2020)

Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation
por: Martinez, Chloe-Anne, et al.
Publicado: (2022)

Danlou Tablets Inhibit Atherosclerosis in Apolipoprotein E-Deficient Mice by Inducing Macrophage Autophagy: The Role of the PI3K-Akt-mTOR Pathway
por: Liu, Chunping, et al.
Publicado: (2021)

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
por: Scholz, Carsten C., et al.
Publicado: (2016)

Intermittent Hypoxia-Induced Cardiomyocyte Death Is Mediated by HIF-1 Dependent MAM Disruption
por: Moulin, Sophie, et al.
Publicado: (2022)

Danlou Tablet Activates Autophagy of Vascular Adventitial Fibroblasts Through PI3K/Akt/mTOR to Protect Cells From Damage Caused by Atherosclerosis
por: Wang, Li, et al.
Publicado: (2021)

Effect of intermittent hypoxia on the cardiac HIF-1/VEGF pathway in experimental type 1 diabetes mellitus
por: Güzel, Derya, et al.
Publicado: (2016)

Knockdown of hypoxia-inducible factor 1-alpha (HIF1α) interferes with angiopoietin-like protein 2 (ANGPTL2) to attenuate high glucose-triggered hypoxia/reoxygenation injury in cardiomyocytes
por: Chen, Weiguo, et al.
Publicado: (2022)

HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
por: Nanduri, Jayasri, et al.
Publicado: (2015)

Exogenous Ang-(1-7) inhibits autophagy via HIF-1α/THBS1/BECN1 axis to alleviate chronic intermittent hypoxia-enhanced airway remodelling of asthma
por: Zhou, Jian Ping, et al.
Publicado: (2023)

Efficacy of Danlou Tablet in Patients with Non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Results from a Multicentre, Placebo-Controlled, Randomized Trial
por: Wang, Lei, et al.
Publicado: (2016)

Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1
por: Pickel, Christina, et al.
Publicado: (2019)

Neurocognitive and Synaptic Potentiation Deficits Are Mitigated by Inhibition of HIF1a Signaling following Intermittent Hypoxia in Rodents
por: Carney, Rosalind S.E.
Publicado: (2020)

Effect of chronic intermittent hypoxia-induced HIF-1α/ATAD2 expression on lung cancer stemness
por: Hao, Shengyu, et al.
Publicado: (2022)

Differential Impact of Intermittent vs. Sustained Hypoxia on HIF-1, VEGF and Proliferation of HepG2 Cells
por: Minoves, Mélanie, et al.
Publicado: (2023)

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains
por: Yang, Ming, et al.
Publicado: (2011)

Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells
por: Bai, Yu, et al.
Publicado: (2021)

Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors
por: Price, Christopher, et al.
Publicado: (2017)

Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3
por: Ten, Tensho, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o145om2mcbv131vcp19hms8c9i