Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease

Compound heterozygous familial hypercholesterolemia patients are phenotypically similar to homozygous familial hypercholesterolemia patients, present with significant elevations of low-density lipoprotein cholesterol, and are at risk of cardiovascular disease. Although new treatment options are emer...

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Autores principales: Weintraub, Spencer F., Schillow, Jessica A., Azari, Bani M., Hirsh, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588451/
https://www.ncbi.nlm.nih.gov/pubmed/36299643
http://dx.doi.org/10.1016/j.jaccas.2022.06.021
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author Weintraub, Spencer F.
Schillow, Jessica A.
Azari, Bani M.
Hirsh, Benjamin J.
author_facet Weintraub, Spencer F.
Schillow, Jessica A.
Azari, Bani M.
Hirsh, Benjamin J.
author_sort Weintraub, Spencer F.
collection PubMed
description Compound heterozygous familial hypercholesterolemia patients are phenotypically similar to homozygous familial hypercholesterolemia patients, present with significant elevations of low-density lipoprotein cholesterol, and are at risk of cardiovascular disease. Although new treatment options are emerging, the stepwise approach to the use of different therapies has not been well described. (Level of Difficulty: Intermediate.)
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spelling pubmed-95884512022-10-25 Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease Weintraub, Spencer F. Schillow, Jessica A. Azari, Bani M. Hirsh, Benjamin J. JACC Case Rep Case Report Compound heterozygous familial hypercholesterolemia patients are phenotypically similar to homozygous familial hypercholesterolemia patients, present with significant elevations of low-density lipoprotein cholesterol, and are at risk of cardiovascular disease. Although new treatment options are emerging, the stepwise approach to the use of different therapies has not been well described. (Level of Difficulty: Intermediate.) Elsevier 2022-10-19 /pmc/articles/PMC9588451/ /pubmed/36299643 http://dx.doi.org/10.1016/j.jaccas.2022.06.021 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Weintraub, Spencer F.
Schillow, Jessica A.
Azari, Bani M.
Hirsh, Benjamin J.
Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease
title Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease
title_full Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease
title_fullStr Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease
title_full_unstemmed Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease
title_short Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease
title_sort implementation of novel lipid therapies in a refractory heterozygous familial hypercholesterolemia patient with atherosclerotic disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588451/
https://www.ncbi.nlm.nih.gov/pubmed/36299643
http://dx.doi.org/10.1016/j.jaccas.2022.06.021
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