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First-in-human study of WT1 recombinant protein vaccination in elderly patients with AML in remission: a single-center experience
Wilms’ tumor 1 (WT1) protein is highly immunogenic and overexpressed in acute myeloid leukemia (AML), consequently ranked as a promising target for novel immunotherapeutic strategies. Here we report our experience of a phase I/II clinical trial (NCT01051063) of a vaccination strategy based on WT1 re...
Autores principales: | Kreutmair, Stefanie, Pfeifer, Dietmar, Waterhouse, Miguel, Takács, Ferenc, Graessel, Linda, Döhner, Konstanze, Duyster, Justus, Illert, Anna Lena, Frey, Anna-Verena, Schmitt, Michael, Lübbert, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588470/ https://www.ncbi.nlm.nih.gov/pubmed/35476127 http://dx.doi.org/10.1007/s00262-022-03202-8 |
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