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Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes

OBJECTIVE: To examine the association between household food insecurity (HFI), glycemic control, severe hypoglycemia and diabetic ketoacidosis (DKA) among youth and young adults (YYA) with youth‐onset type 2 diabetes. RESEARCH DESIGN AND METHODS: This cross‐sectional study included 395 YYA with type...

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Autores principales: Reid, Lauren A., Mendoza, Jason A., Merchant, Anwar T., Geraci, Marco, Reboussin, Beth A., Malik, Faisal S., Ellyson, Alice M., Dabelea, Dana, Merjaneh, Lina, Marcovina, Santica M., Lustigova, Eva, Lawrence, Jean M., Liese, Angela D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588511/
https://www.ncbi.nlm.nih.gov/pubmed/35752872
http://dx.doi.org/10.1111/pedi.13386
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author Reid, Lauren A.
Mendoza, Jason A.
Merchant, Anwar T.
Geraci, Marco
Reboussin, Beth A.
Malik, Faisal S.
Ellyson, Alice M.
Dabelea, Dana
Merjaneh, Lina
Marcovina, Santica M.
Lustigova, Eva
Lawrence, Jean M.
Liese, Angela D.
author_facet Reid, Lauren A.
Mendoza, Jason A.
Merchant, Anwar T.
Geraci, Marco
Reboussin, Beth A.
Malik, Faisal S.
Ellyson, Alice M.
Dabelea, Dana
Merjaneh, Lina
Marcovina, Santica M.
Lustigova, Eva
Lawrence, Jean M.
Liese, Angela D.
author_sort Reid, Lauren A.
collection PubMed
description OBJECTIVE: To examine the association between household food insecurity (HFI), glycemic control, severe hypoglycemia and diabetic ketoacidosis (DKA) among youth and young adults (YYA) with youth‐onset type 2 diabetes. RESEARCH DESIGN AND METHODS: This cross‐sectional study included 395 YYA with type 2 diabetes from the SEARCH for Diabetes in Youth Study (2015–2019). HFI was reported by young adult participants or parents of minor participants via the US Household Food Security Survey Module. Glycemic control was assessed by HbA(1c) and analyzed as a continuous and categorical variable (optimal: <7.0%, suboptimal: ≥7.0%–9.0%, poor: >9.0%). Acute complications included self‐reported severe hypoglycemia or DKA in the last 12 months. Adjusted logistic and linear regression were used for binary and continuous outcomes, respectively. RESULTS: Approximately 31% reported HFI in the past 12 months. Mean HbA(1c) among those with HFI was 9.2% compared to 9.5% without HFI. Of those with HFI, 56% had an HbA(1c) >9.0% compared to 55% without HFI. Adjusted models showed no associations between HFI and glycemic control. Of those with HFI, 14.4% reported experiencing DKA and 4.7% reported severe hypoglycemia. YYA with HFI had 3.08 times (95% CI: 1.18–8.06) the odds of experiencing DKA as those without HFI. There was no association between HFI and severe hypoglycemia. CONCLUSIONS: HFI was associated with markedly increased odds of DKA but not with glycemic control or severe hypoglycemia. Future research among YYA with type 2 diabetes should evaluate longitudinally whether alleviating HFI reduces DKA.
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spelling pubmed-95885112022-12-30 Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes Reid, Lauren A. Mendoza, Jason A. Merchant, Anwar T. Geraci, Marco Reboussin, Beth A. Malik, Faisal S. Ellyson, Alice M. Dabelea, Dana Merjaneh, Lina Marcovina, Santica M. Lustigova, Eva Lawrence, Jean M. Liese, Angela D. Pediatr Diabetes Obesity/Insulin Resistance, Type 2 Diabetes OBJECTIVE: To examine the association between household food insecurity (HFI), glycemic control, severe hypoglycemia and diabetic ketoacidosis (DKA) among youth and young adults (YYA) with youth‐onset type 2 diabetes. RESEARCH DESIGN AND METHODS: This cross‐sectional study included 395 YYA with type 2 diabetes from the SEARCH for Diabetes in Youth Study (2015–2019). HFI was reported by young adult participants or parents of minor participants via the US Household Food Security Survey Module. Glycemic control was assessed by HbA(1c) and analyzed as a continuous and categorical variable (optimal: <7.0%, suboptimal: ≥7.0%–9.0%, poor: >9.0%). Acute complications included self‐reported severe hypoglycemia or DKA in the last 12 months. Adjusted logistic and linear regression were used for binary and continuous outcomes, respectively. RESULTS: Approximately 31% reported HFI in the past 12 months. Mean HbA(1c) among those with HFI was 9.2% compared to 9.5% without HFI. Of those with HFI, 56% had an HbA(1c) >9.0% compared to 55% without HFI. Adjusted models showed no associations between HFI and glycemic control. Of those with HFI, 14.4% reported experiencing DKA and 4.7% reported severe hypoglycemia. YYA with HFI had 3.08 times (95% CI: 1.18–8.06) the odds of experiencing DKA as those without HFI. There was no association between HFI and severe hypoglycemia. CONCLUSIONS: HFI was associated with markedly increased odds of DKA but not with glycemic control or severe hypoglycemia. Future research among YYA with type 2 diabetes should evaluate longitudinally whether alleviating HFI reduces DKA. John Wiley & Sons A/S 2022-07-10 2022-11 /pmc/articles/PMC9588511/ /pubmed/35752872 http://dx.doi.org/10.1111/pedi.13386 Text en © 2022 The Authors. Pediatric Diabetes published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Obesity/Insulin Resistance, Type 2 Diabetes
Reid, Lauren A.
Mendoza, Jason A.
Merchant, Anwar T.
Geraci, Marco
Reboussin, Beth A.
Malik, Faisal S.
Ellyson, Alice M.
Dabelea, Dana
Merjaneh, Lina
Marcovina, Santica M.
Lustigova, Eva
Lawrence, Jean M.
Liese, Angela D.
Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
title Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
title_full Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
title_fullStr Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
title_full_unstemmed Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
title_short Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
title_sort household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with youth‐onset type 2 diabetes
topic Obesity/Insulin Resistance, Type 2 Diabetes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588511/
https://www.ncbi.nlm.nih.gov/pubmed/35752872
http://dx.doi.org/10.1111/pedi.13386
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