Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure

We describe a case referred for worsening hypercholesterolemia in the setting of atorvastatin and fenofibrate-induced liver injury. The patient reported neurological complaints attributed to hyperviscosity syndrome (induced by lipoprotein-X and lipoprotein-Z). Hepatic recovery was associated with re...

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Autores principales: Waksman, Ori, Cho, Daniel J., Kim, HyoungSup, Otvos, James D., Rosenson, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588591/
https://www.ncbi.nlm.nih.gov/pubmed/36299645
http://dx.doi.org/10.1016/j.jaccas.2022.09.001
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author Waksman, Ori
Cho, Daniel J.
Kim, HyoungSup
Otvos, James D.
Rosenson, Robert S.
author_facet Waksman, Ori
Cho, Daniel J.
Kim, HyoungSup
Otvos, James D.
Rosenson, Robert S.
author_sort Waksman, Ori
collection PubMed
description We describe a case referred for worsening hypercholesterolemia in the setting of atorvastatin and fenofibrate-induced liver injury. The patient reported neurological complaints attributed to hyperviscosity syndrome (induced by lipoprotein-X and lipoprotein-Z). Hepatic recovery was associated with reduction of whole blood viscosity and amelioration of neurological symptoms. (Level of Difficulty: Advanced.)
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spelling pubmed-95885912022-10-25 Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure Waksman, Ori Cho, Daniel J. Kim, HyoungSup Otvos, James D. Rosenson, Robert S. JACC Case Rep Case Report We describe a case referred for worsening hypercholesterolemia in the setting of atorvastatin and fenofibrate-induced liver injury. The patient reported neurological complaints attributed to hyperviscosity syndrome (induced by lipoprotein-X and lipoprotein-Z). Hepatic recovery was associated with reduction of whole blood viscosity and amelioration of neurological symptoms. (Level of Difficulty: Advanced.) Elsevier 2022-10-19 /pmc/articles/PMC9588591/ /pubmed/36299645 http://dx.doi.org/10.1016/j.jaccas.2022.09.001 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Waksman, Ori
Cho, Daniel J.
Kim, HyoungSup
Otvos, James D.
Rosenson, Robert S.
Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure
title Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure
title_full Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure
title_fullStr Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure
title_full_unstemmed Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure
title_short Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure
title_sort lipoprotein-x and lipoprotein-z induced hyperviscosity syndrome in the setting of cholestatic liver failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588591/
https://www.ncbi.nlm.nih.gov/pubmed/36299645
http://dx.doi.org/10.1016/j.jaccas.2022.09.001
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