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Combined evaluation of both WEE1 and phosphorylated cyclin dependent kinase 1 expressions in oral squamous cell carcinomas predicts cancer recurrence and progression

BACKGROUND/PURPOSE: WEE1 is a mitotic inhibitor at G2 checkpoint of the cell cycle that negatively regulates cyclin-dependent kinase 1 (CDK1) through inhibitory phosphorylation. This study assessed whether the expressions of both WEE1 and phosphorylated CDK1 in specimens of oral squamous cell carcin...

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Detalles Bibliográficos
Autores principales: Wu, Yu-Hsueh, Yu-Fong Chang, Julia, Chiang, Chun-Pin, Wang, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588842/
https://www.ncbi.nlm.nih.gov/pubmed/36299328
http://dx.doi.org/10.1016/j.jds.2022.08.009