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Intraperitoneal alpha therapy with (224)Ra-labeled microparticles combined with chemotherapy in an ovarian cancer mouse model

A novel alpha-therapy consisting of (224)Ra-labeled calcium carbonate microparticles ((224)Ra-CaCO(3)-MP) has been designed to treat micrometastatic peritoneal disease via intraperitoneal (IP) administration. This preclinical study aimed to evaluate its efficacy and tolerability when given as a sing...

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Detalles Bibliográficos
Autores principales:	Wouters, Roxanne, Westrøm, Sara, Berckmans, Yani, Riva, Matteo, Ceusters, Jolien, Bønsdorff, Tina B., Vergote, Ignace, Coosemans, An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588927/ https://www.ncbi.nlm.nih.gov/pubmed/36300186 http://dx.doi.org/10.3389/fmed.2022.995325

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