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Conductive fibers for biomedical applications
Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues. Thus, various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration, or to interface with cells or tissue/organ surf...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588989/ https://www.ncbi.nlm.nih.gov/pubmed/36311045 http://dx.doi.org/10.1016/j.bioactmat.2022.10.014 |
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author | Wei, Leqian Wang, Shasha Shan, Mengqi Li, Yimeng Wang, Yongliang Wang, Fujun Wang, Lu Mao, Jifu |
author_facet | Wei, Leqian Wang, Shasha Shan, Mengqi Li, Yimeng Wang, Yongliang Wang, Fujun Wang, Lu Mao, Jifu |
author_sort | Wei, Leqian |
collection | PubMed |
description | Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues. Thus, various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration, or to interface with cells or tissue/organ surfaces to acquire physiological status via electrical signals. Benefiting from the outstanding advantages of flexibility, structural diversity, customizable mechanical properties, and tunable distribution of conductive components, conductive fibers are able to avoid the damage-inducing mechanical mismatch between the construct and the biological environment, in return to ensure stable functioning of such constructs during physiological deformation. Herein, this review starts by presenting current fabrication technologies of conductive fibers including wet spinning, microfluidic spinning, electrospinning and 3D printing as well as surface modification on fibers and fiber assemblies. To provide an update on the biomedical applications of conductive fibers and fiber assemblies, we further elaborate conductive fibrous constructs utilized in tissue engineering and regeneration, implantable healthcare bioelectronics, and wearable healthcare bioelectronics. To conclude, current challenges and future perspectives of biomedical electronic constructs built by conductive fibers are discussed. |
format | Online Article Text |
id | pubmed-9588989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-95889892022-10-27 Conductive fibers for biomedical applications Wei, Leqian Wang, Shasha Shan, Mengqi Li, Yimeng Wang, Yongliang Wang, Fujun Wang, Lu Mao, Jifu Bioact Mater Review Article Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues. Thus, various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration, or to interface with cells or tissue/organ surfaces to acquire physiological status via electrical signals. Benefiting from the outstanding advantages of flexibility, structural diversity, customizable mechanical properties, and tunable distribution of conductive components, conductive fibers are able to avoid the damage-inducing mechanical mismatch between the construct and the biological environment, in return to ensure stable functioning of such constructs during physiological deformation. Herein, this review starts by presenting current fabrication technologies of conductive fibers including wet spinning, microfluidic spinning, electrospinning and 3D printing as well as surface modification on fibers and fiber assemblies. To provide an update on the biomedical applications of conductive fibers and fiber assemblies, we further elaborate conductive fibrous constructs utilized in tissue engineering and regeneration, implantable healthcare bioelectronics, and wearable healthcare bioelectronics. To conclude, current challenges and future perspectives of biomedical electronic constructs built by conductive fibers are discussed. KeAi Publishing 2022-10-20 /pmc/articles/PMC9588989/ /pubmed/36311045 http://dx.doi.org/10.1016/j.bioactmat.2022.10.014 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Wei, Leqian Wang, Shasha Shan, Mengqi Li, Yimeng Wang, Yongliang Wang, Fujun Wang, Lu Mao, Jifu Conductive fibers for biomedical applications |
title | Conductive fibers for biomedical applications |
title_full | Conductive fibers for biomedical applications |
title_fullStr | Conductive fibers for biomedical applications |
title_full_unstemmed | Conductive fibers for biomedical applications |
title_short | Conductive fibers for biomedical applications |
title_sort | conductive fibers for biomedical applications |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588989/ https://www.ncbi.nlm.nih.gov/pubmed/36311045 http://dx.doi.org/10.1016/j.bioactmat.2022.10.014 |
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