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Conductive fibers for biomedical applications

Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues. Thus, various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration, or to interface with cells or tissue/organ surf...

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Detalles Bibliográficos
Autores principales: Wei, Leqian, Wang, Shasha, Shan, Mengqi, Li, Yimeng, Wang, Yongliang, Wang, Fujun, Wang, Lu, Mao, Jifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588989/
https://www.ncbi.nlm.nih.gov/pubmed/36311045
http://dx.doi.org/10.1016/j.bioactmat.2022.10.014
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author Wei, Leqian
Wang, Shasha
Shan, Mengqi
Li, Yimeng
Wang, Yongliang
Wang, Fujun
Wang, Lu
Mao, Jifu
author_facet Wei, Leqian
Wang, Shasha
Shan, Mengqi
Li, Yimeng
Wang, Yongliang
Wang, Fujun
Wang, Lu
Mao, Jifu
author_sort Wei, Leqian
collection PubMed
description Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues. Thus, various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration, or to interface with cells or tissue/organ surfaces to acquire physiological status via electrical signals. Benefiting from the outstanding advantages of flexibility, structural diversity, customizable mechanical properties, and tunable distribution of conductive components, conductive fibers are able to avoid the damage-inducing mechanical mismatch between the construct and the biological environment, in return to ensure stable functioning of such constructs during physiological deformation. Herein, this review starts by presenting current fabrication technologies of conductive fibers including wet spinning, microfluidic spinning, electrospinning and 3D printing as well as surface modification on fibers and fiber assemblies. To provide an update on the biomedical applications of conductive fibers and fiber assemblies, we further elaborate conductive fibrous constructs utilized in tissue engineering and regeneration, implantable healthcare bioelectronics, and wearable healthcare bioelectronics. To conclude, current challenges and future perspectives of biomedical electronic constructs built by conductive fibers are discussed.
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spelling pubmed-95889892022-10-27 Conductive fibers for biomedical applications Wei, Leqian Wang, Shasha Shan, Mengqi Li, Yimeng Wang, Yongliang Wang, Fujun Wang, Lu Mao, Jifu Bioact Mater Review Article Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues. Thus, various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration, or to interface with cells or tissue/organ surfaces to acquire physiological status via electrical signals. Benefiting from the outstanding advantages of flexibility, structural diversity, customizable mechanical properties, and tunable distribution of conductive components, conductive fibers are able to avoid the damage-inducing mechanical mismatch between the construct and the biological environment, in return to ensure stable functioning of such constructs during physiological deformation. Herein, this review starts by presenting current fabrication technologies of conductive fibers including wet spinning, microfluidic spinning, electrospinning and 3D printing as well as surface modification on fibers and fiber assemblies. To provide an update on the biomedical applications of conductive fibers and fiber assemblies, we further elaborate conductive fibrous constructs utilized in tissue engineering and regeneration, implantable healthcare bioelectronics, and wearable healthcare bioelectronics. To conclude, current challenges and future perspectives of biomedical electronic constructs built by conductive fibers are discussed. KeAi Publishing 2022-10-20 /pmc/articles/PMC9588989/ /pubmed/36311045 http://dx.doi.org/10.1016/j.bioactmat.2022.10.014 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Wei, Leqian
Wang, Shasha
Shan, Mengqi
Li, Yimeng
Wang, Yongliang
Wang, Fujun
Wang, Lu
Mao, Jifu
Conductive fibers for biomedical applications
title Conductive fibers for biomedical applications
title_full Conductive fibers for biomedical applications
title_fullStr Conductive fibers for biomedical applications
title_full_unstemmed Conductive fibers for biomedical applications
title_short Conductive fibers for biomedical applications
title_sort conductive fibers for biomedical applications
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588989/
https://www.ncbi.nlm.nih.gov/pubmed/36311045
http://dx.doi.org/10.1016/j.bioactmat.2022.10.014
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