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miR-30a inhibits the osteogenic differentiation of the tibia-derived MSCs in congenital pseudarthrosis via targeting HOXD8

BACKGROUND: Congenital pseudarthrosis of the tibia (CPT) is an uncommon congenital deformity and a special subtype of bone nonunion. The lower ability of osteogenic differentiation in CPT-derived mesenchymal stem cells (MSCs) could result in progression of CPT, and miR-30a could inhibit osteogenic d...

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Detalles Bibliográficos
Autores principales: Ye, Weihua, Huang, Yiyong, Zhu, Guanghui, Yan, An, Liu, Yaoxi, Xiao, Han, Mei, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588990/
https://www.ncbi.nlm.nih.gov/pubmed/36313394
http://dx.doi.org/10.1016/j.reth.2022.09.005