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Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
Environmental and genetic factors cause defects in pancreatic islets driving type 2 diabetes (T2D) together with the progression of multi-tissue insulin resistance. Mass spectrometry proteomics on samples from five key metabolic tissues of a cross-sectional cohort of 43 multi-organ donors provides d...
Autores principales: | Diamanti, Klev, Cavalli, Marco, Pereira, Maria J., Pan, Gang, Castillejo-López, Casimiro, Kumar, Chanchal, Mundt, Filip, Komorowski, Jan, Deshmukh, Atul S., Mann, Matthias, Korsgren, Olle, Eriksson, Jan W., Wadelius, Claes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589007/ https://www.ncbi.nlm.nih.gov/pubmed/36198307 http://dx.doi.org/10.1016/j.xcrm.2022.100763 |
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