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Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Environmental and genetic factors cause defects in pancreatic islets driving type 2 diabetes (T2D) together with the progression of multi-tissue insulin resistance. Mass spectrometry proteomics on samples from five key metabolic tissues of a cross-sectional cohort of 43 multi-organ donors provides d...

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Detalles Bibliográficos
Autores principales: Diamanti, Klev, Cavalli, Marco, Pereira, Maria J., Pan, Gang, Castillejo-López, Casimiro, Kumar, Chanchal, Mundt, Filip, Komorowski, Jan, Deshmukh, Atul S., Mann, Matthias, Korsgren, Olle, Eriksson, Jan W., Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589007/
https://www.ncbi.nlm.nih.gov/pubmed/36198307
http://dx.doi.org/10.1016/j.xcrm.2022.100763

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