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Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study

Aging is a very diverse process: successful agers retain most cognitive functioning, while others experience mild to severe cognitive decline. This decline may eventually negatively impact one’s everyday activities. Therefore, scientists must develop approaches to counteract or, at least, slow down...

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Autores principales: Assecondi, Sara, Hu, Rong, Kroeker, Jacob, Eskes, Gail, Shapiro, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589058/
https://www.ncbi.nlm.nih.gov/pubmed/36299611
http://dx.doi.org/10.3389/fnagi.2022.1009262
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author Assecondi, Sara
Hu, Rong
Kroeker, Jacob
Eskes, Gail
Shapiro, Kim
author_facet Assecondi, Sara
Hu, Rong
Kroeker, Jacob
Eskes, Gail
Shapiro, Kim
author_sort Assecondi, Sara
collection PubMed
description Aging is a very diverse process: successful agers retain most cognitive functioning, while others experience mild to severe cognitive decline. This decline may eventually negatively impact one’s everyday activities. Therefore, scientists must develop approaches to counteract or, at least, slow down the negative change in cognitive performance of aging individuals. Combining cognitive training and transcranial direct current stimulation (tDCS) is a promising approach that capitalizes on the plasticity of brain networks. However, the efficacy of combined methods depends on individual characteristics, such as the cognitive and emotional state of the individual entering the training program. In this report, we explored the effectiveness of working memory training, combined with tDCS to the right dorsolateral prefrontal cortex (DLPFC), to manipulate working memory performance in older individuals. We hypothesized that individuals with lower working memory capacity would benefit the most from the combined regimen. Thirty older adults took part in a 5-day combined regimen. Before and after the training, we evaluated participants’ working memory performance with five working memory tasks. We found that individual characteristics influenced the outcome of combined cognitive training and tDCS regimens, with the intervention selectively benefiting old-old adults with lower working memory capacity. Future work should consider developing individualized treatments by considering individual differences in cognitive profiles.
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spelling pubmed-95890582022-10-25 Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study Assecondi, Sara Hu, Rong Kroeker, Jacob Eskes, Gail Shapiro, Kim Front Aging Neurosci Neuroscience Aging is a very diverse process: successful agers retain most cognitive functioning, while others experience mild to severe cognitive decline. This decline may eventually negatively impact one’s everyday activities. Therefore, scientists must develop approaches to counteract or, at least, slow down the negative change in cognitive performance of aging individuals. Combining cognitive training and transcranial direct current stimulation (tDCS) is a promising approach that capitalizes on the plasticity of brain networks. However, the efficacy of combined methods depends on individual characteristics, such as the cognitive and emotional state of the individual entering the training program. In this report, we explored the effectiveness of working memory training, combined with tDCS to the right dorsolateral prefrontal cortex (DLPFC), to manipulate working memory performance in older individuals. We hypothesized that individuals with lower working memory capacity would benefit the most from the combined regimen. Thirty older adults took part in a 5-day combined regimen. Before and after the training, we evaluated participants’ working memory performance with five working memory tasks. We found that individual characteristics influenced the outcome of combined cognitive training and tDCS regimens, with the intervention selectively benefiting old-old adults with lower working memory capacity. Future work should consider developing individualized treatments by considering individual differences in cognitive profiles. Frontiers Media S.A. 2022-10-10 /pmc/articles/PMC9589058/ /pubmed/36299611 http://dx.doi.org/10.3389/fnagi.2022.1009262 Text en Copyright © 2022 Assecondi, Hu, Kroeker, Eskes and Shapiro. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Assecondi, Sara
Hu, Rong
Kroeker, Jacob
Eskes, Gail
Shapiro, Kim
Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study
title Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study
title_full Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study
title_fullStr Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study
title_full_unstemmed Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study
title_short Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study
title_sort older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: a preliminary study
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589058/
https://www.ncbi.nlm.nih.gov/pubmed/36299611
http://dx.doi.org/10.3389/fnagi.2022.1009262
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