Reducing misclassification bias in severe malaria research

By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.(1) increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification.

Detalles Bibliográficos
Autores principales: Ippolito, Matthew M., Robinson, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589118/
https://www.ncbi.nlm.nih.gov/pubmed/36260989
http://dx.doi.org/10.1016/j.xcrm.2022.100789
Descripción
Sumario:By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.(1) increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification.

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