Cargando…
Reducing misclassification bias in severe malaria research
By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.(1) increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification.
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589118/ https://www.ncbi.nlm.nih.gov/pubmed/36260989 http://dx.doi.org/10.1016/j.xcrm.2022.100789 |
| _version_ | 1784814229932474368 |
|---|---|
| author | Ippolito, Matthew M. Robinson, Matthew L. |
| author_facet | Ippolito, Matthew M. Robinson, Matthew L. |
| author_sort | Ippolito, Matthew M. |
| collection | PubMed |
| description | By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.(1) increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification. |
| format | Online Article Text |
| id | pubmed-9589118 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-95891182022-10-25 Reducing misclassification bias in severe malaria research Ippolito, Matthew M. Robinson, Matthew L. Cell Rep Med Spotlight By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.(1) increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification. Elsevier 2022-10-18 /pmc/articles/PMC9589118/ /pubmed/36260989 http://dx.doi.org/10.1016/j.xcrm.2022.100789 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Spotlight Ippolito, Matthew M. Robinson, Matthew L. Reducing misclassification bias in severe malaria research |
| title | Reducing misclassification bias in severe malaria research |
| title_full | Reducing misclassification bias in severe malaria research |
| title_fullStr | Reducing misclassification bias in severe malaria research |
| title_full_unstemmed | Reducing misclassification bias in severe malaria research |
| title_short | Reducing misclassification bias in severe malaria research |
| title_sort | reducing misclassification bias in severe malaria research |
| topic | Spotlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589118/ https://www.ncbi.nlm.nih.gov/pubmed/36260989 http://dx.doi.org/10.1016/j.xcrm.2022.100789 |
| work_keys_str_mv | AT ippolitomatthewm reducingmisclassificationbiasinseveremalariaresearch AT robinsonmatthewl reducingmisclassificationbiasinseveremalariaresearch |