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Two types of biomarker-dependent chemo-immunotherapy for pancreatic cancer?

Padron et al.(1) studied the combination of chemotherapy (gemcitabine and nab-paclitaxel) with either an anti-PD1 (nivolumab) or an anti-CD40 (sotigalimab) antibody in metastatic pancreatic cancer. They showed clinical benefit in individuals with unique biomarkers for each treatment combination

Detalles Bibliográficos
Autor principal: Melief, Cornelis J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589119/
https://www.ncbi.nlm.nih.gov/pubmed/36260984
http://dx.doi.org/10.1016/j.xcrm.2022.100788
Descripción
Sumario:Padron et al.(1) studied the combination of chemotherapy (gemcitabine and nab-paclitaxel) with either an anti-PD1 (nivolumab) or an anti-CD40 (sotigalimab) antibody in metastatic pancreatic cancer. They showed clinical benefit in individuals with unique biomarkers for each treatment combination