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Inhibition of IRAK 1/4 alleviates colitis by inhibiting TLR 4/NF-κB pathway and protecting the intestinal barrier

Interleukin-1 receptor-associated kinase 1/4 (IRAK1/4) is the main kinase of the toll-like receptor (TLR)-mediated pathway, considered a new target for treating inflammatory diseases. Studies showed a significant correlation between TLRs and inflammatory responses in ulcerative colitis. Therefore, i...

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Detalles Bibliográficos
Autores principales:	Yan, Bo, Li, Xiangjie, Zhou, Linxiang, Qiao, Yuqing, Wu, Jing, Zha, Lanlan, Liu, Peilu, Peng, Shuai, Wu, Baixin, Yu, Xiaoyun, Shen, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589302/ https://www.ncbi.nlm.nih.gov/pubmed/35699749 http://dx.doi.org/10.17305/bjbms.2022.7348

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