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Analysis of real-world data and a mouse model indicates that pirfenidone causes pellagra

BACKGROUND: Pirfenidone (PFD) is widely used in patients with idiopathic pulmonary fibrosis (IPF) and its adverse effects, such as nausea and photosensitivity, are well known. Many patients with IPF have reduced doses or even cessation of PFD because of its side-effects. No solutions have been found...

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Detalles Bibliográficos
Autores principales: Kuronuma, Koji, Susai, Natsumi, Kuroita, Tomohiro, Yamamoto, Hiroki, Yoshioka, Takeshi, Kaneko, Shuji, Chiba, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589320/
https://www.ncbi.nlm.nih.gov/pubmed/36299372
http://dx.doi.org/10.1183/23120541.00245-2022