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Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination

Vaccination using optimized strategies may increase response rates to immune checkpoint inhibitors (ICI) in some tumors. To enhance vaccine potency and improve thus responses to ICI, we analyzed the gene expression profile of an immunosuppressive dendritic cell (DC) population induced during vaccina...

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Detalles Bibliográficos
Autores principales:	Repáraz, David, Ruiz, Marta, Silva, Leyre, Aparicio, Belén, Egea, Josune, Guruceaga, Elizabeth, Ajona, Daniel, Senent, Yaiza, Conde, Enrique, Navarro, Flor, Barace, Sergio, Alignani, Diego, Hervás-Stubbs, Sandra, Lasarte, Juan José, Llopiz, Diana, Sarobe, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589451/ https://www.ncbi.nlm.nih.gov/pubmed/36300124 http://dx.doi.org/10.3389/fimmu.2022.991311

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