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High-Resolution Epitope Mapping and Affinity Binding Analysis Comparing a New Anti-Human LAG3 Rabbit Antibody Clone to the Commonly Used Mouse 17B4 Clone

Lymphocyte activation gene 3 (LAG3) is a T cell inhibitory receptor that promotes tumor cell immune escape and is a potential target for cancer diagnostic and immunotherapeutic applications. We used automated capillary electrophoresis (ACE), surface plasmon resonance (SPR), and immunohistochemistry...

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Detalles Bibliográficos
Autores principales: Warren, P. Daniel, Dodson, Mark S., Smith, Margaret H., Landowski, Terry H., Palting, John Douglas, Towne, Penny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589981/
https://www.ncbi.nlm.nih.gov/pubmed/36278613
http://dx.doi.org/10.3390/antib11040060

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