Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership

After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-clinical development, and operational challenge...

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Detalles Bibliográficos
Autores principales: Bernhard, Sonja, Kaiser, Marcel, Burri, Christian, Mäser, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589988/
https://www.ncbi.nlm.nih.gov/pubmed/36278589
http://dx.doi.org/10.3390/diseases10040090

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