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Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis

Senile gluteal dermatosis (SGD) is a common but seldom recognized condition. It is characterized clinically by unilateral or bilateral hyperkeratotic, lichenified plaques on the gluteal area, being attributed to prolonged sitting, particularly in the elderly. SGD also encompasses the recently propos...

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Autores principales: Liang, Michelle Weiting, Lim, Joel H. L., Chia, Hui Yi, Tee, Shang-Ian, Lee, Joyce S. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590008/
https://www.ncbi.nlm.nih.gov/pubmed/36278541
http://dx.doi.org/10.3390/dermatopathology9040040
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author Liang, Michelle Weiting
Lim, Joel H. L.
Chia, Hui Yi
Tee, Shang-Ian
Lee, Joyce S. S.
author_facet Liang, Michelle Weiting
Lim, Joel H. L.
Chia, Hui Yi
Tee, Shang-Ian
Lee, Joyce S. S.
author_sort Liang, Michelle Weiting
collection PubMed
description Senile gluteal dermatosis (SGD) is a common but seldom recognized condition. It is characterized clinically by unilateral or bilateral hyperkeratotic, lichenified plaques on the gluteal area, being attributed to prolonged sitting, particularly in the elderly. SGD also encompasses the recently proposed entity of prurigiform angiomatosis. Histologically, there are features of lichenification, such as epidermal hyperplasia and a preserved granular layer, with prominent dermal angioproliferation. We report 4 cases of this condition as well as novel findings of variably increased mast cells and superficial lymphatic vessels in addition to the proliferation of dermal blood vessels. We propose a unifying name for Reactive Epidermal hyperplasia and Angiogenesis of the Rear (REAR) to encapsulate the characteristic clinical and histological features of this distinct entity.
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spelling pubmed-95900082022-10-25 Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis Liang, Michelle Weiting Lim, Joel H. L. Chia, Hui Yi Tee, Shang-Ian Lee, Joyce S. S. Dermatopathology (Basel) Case Report Senile gluteal dermatosis (SGD) is a common but seldom recognized condition. It is characterized clinically by unilateral or bilateral hyperkeratotic, lichenified plaques on the gluteal area, being attributed to prolonged sitting, particularly in the elderly. SGD also encompasses the recently proposed entity of prurigiform angiomatosis. Histologically, there are features of lichenification, such as epidermal hyperplasia and a preserved granular layer, with prominent dermal angioproliferation. We report 4 cases of this condition as well as novel findings of variably increased mast cells and superficial lymphatic vessels in addition to the proliferation of dermal blood vessels. We propose a unifying name for Reactive Epidermal hyperplasia and Angiogenesis of the Rear (REAR) to encapsulate the characteristic clinical and histological features of this distinct entity. MDPI 2022-10-13 /pmc/articles/PMC9590008/ /pubmed/36278541 http://dx.doi.org/10.3390/dermatopathology9040040 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Liang, Michelle Weiting
Lim, Joel H. L.
Chia, Hui Yi
Tee, Shang-Ian
Lee, Joyce S. S.
Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis
title Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis
title_full Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis
title_fullStr Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis
title_full_unstemmed Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis
title_short Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis
title_sort reactive epidermal hyperplasia and angiogenesis of the rear (rear): a proposed unifying name for senile gluteal dermatosis and prurigiform angiomatosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590008/
https://www.ncbi.nlm.nih.gov/pubmed/36278541
http://dx.doi.org/10.3390/dermatopathology9040040
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