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Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts

This work presents the preparation of bioactive glasses 70SiO(2)–(26 − x)CaO–4P(2)O(5)–xAg(2)O (with x = 0, 1, 3, 10 mol%) by a modified sol–gel method with reduced synthesis time based on hydrothermal reaction in a medium without acid or base catalysts. The synthetic materials were characterized by...

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Autores principales: Hoa, Bui Thi, Phuc, Le Hong, Hien, Nguyen Quan, Vinh, Le Khanh, Tien, Nguyen Anh, Hiep, Dang Tan, Vi, Vo Thuy, Ly, Dang Ngoc, Long, Nguyen Viet, Hieu, Tran Trung, Linh, Le Viet, Minh, Nguyen Tuyet, Xuan Vuong, Bui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590098/
https://www.ncbi.nlm.nih.gov/pubmed/36329943
http://dx.doi.org/10.1039/d2ra05671b
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author Hoa, Bui Thi
Phuc, Le Hong
Hien, Nguyen Quan
Vinh, Le Khanh
Tien, Nguyen Anh
Hiep, Dang Tan
Vi, Vo Thuy
Ly, Dang Ngoc
Long, Nguyen Viet
Hieu, Tran Trung
Linh, Le Viet
Minh, Nguyen Tuyet
Xuan Vuong, Bui
author_facet Hoa, Bui Thi
Phuc, Le Hong
Hien, Nguyen Quan
Vinh, Le Khanh
Tien, Nguyen Anh
Hiep, Dang Tan
Vi, Vo Thuy
Ly, Dang Ngoc
Long, Nguyen Viet
Hieu, Tran Trung
Linh, Le Viet
Minh, Nguyen Tuyet
Xuan Vuong, Bui
author_sort Hoa, Bui Thi
collection PubMed
description This work presents the preparation of bioactive glasses 70SiO(2)–(26 − x)CaO–4P(2)O(5)–xAg(2)O (with x = 0, 1, 3, 10 mol%) by a modified sol–gel method with reduced synthesis time based on hydrothermal reaction in a medium without acid or base catalysts. The synthetic materials were characterized by several physical–chemical techniques such as TG-DSC, XRD, SEM, TEM, and N(2) adsorption/desorption measurement. The analysis data confirmed that the glass sample not containing Ag has a completely amorphous structure, while glass samples containing Ag exhibited a pure phase of metallic nano-silver in the glass amorphous phase. All the synthetic glasses have mesoporous structures with particle sizes of less than 30 nm. The addition of silver to the bioactive glass structure in general did not drastically reduce the specific surface areas and pore volumes of glasses as in previous studies. The bioactivity of the silver-incorporated glasses did not reduce, and even increased in the cases of bioactive glass containing 3, and 10 mol% of Ag(2)O. The biocompatibility of synthetic glasses with fibroblast cells (L-929) was confirmed, even with glass containing high amounts of Ag. Representatively, Ag-incorporated glass samples (sample x = 3, and x = 10) were selected to check the antibacterial ability using bacterial strain Pseudomonas aeruginosa ATCC 27853 (Pa). The obtained results indicated that these glasses exhibited good antibacterial ability to Pseudomonas aeruginosa. Thus, the synthetic method in this study proved to be a fast, environmentally friendly technique for synthesizing Ag-incorporated glass systems. The synthesized glasses show good bioactive, biocompatible, and antibacterial properties.
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spelling pubmed-95900982022-11-02 Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts Hoa, Bui Thi Phuc, Le Hong Hien, Nguyen Quan Vinh, Le Khanh Tien, Nguyen Anh Hiep, Dang Tan Vi, Vo Thuy Ly, Dang Ngoc Long, Nguyen Viet Hieu, Tran Trung Linh, Le Viet Minh, Nguyen Tuyet Xuan Vuong, Bui RSC Adv Chemistry This work presents the preparation of bioactive glasses 70SiO(2)–(26 − x)CaO–4P(2)O(5)–xAg(2)O (with x = 0, 1, 3, 10 mol%) by a modified sol–gel method with reduced synthesis time based on hydrothermal reaction in a medium without acid or base catalysts. The synthetic materials were characterized by several physical–chemical techniques such as TG-DSC, XRD, SEM, TEM, and N(2) adsorption/desorption measurement. The analysis data confirmed that the glass sample not containing Ag has a completely amorphous structure, while glass samples containing Ag exhibited a pure phase of metallic nano-silver in the glass amorphous phase. All the synthetic glasses have mesoporous structures with particle sizes of less than 30 nm. The addition of silver to the bioactive glass structure in general did not drastically reduce the specific surface areas and pore volumes of glasses as in previous studies. The bioactivity of the silver-incorporated glasses did not reduce, and even increased in the cases of bioactive glass containing 3, and 10 mol% of Ag(2)O. The biocompatibility of synthetic glasses with fibroblast cells (L-929) was confirmed, even with glass containing high amounts of Ag. Representatively, Ag-incorporated glass samples (sample x = 3, and x = 10) were selected to check the antibacterial ability using bacterial strain Pseudomonas aeruginosa ATCC 27853 (Pa). The obtained results indicated that these glasses exhibited good antibacterial ability to Pseudomonas aeruginosa. Thus, the synthetic method in this study proved to be a fast, environmentally friendly technique for synthesizing Ag-incorporated glass systems. The synthesized glasses show good bioactive, biocompatible, and antibacterial properties. The Royal Society of Chemistry 2022-10-24 /pmc/articles/PMC9590098/ /pubmed/36329943 http://dx.doi.org/10.1039/d2ra05671b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Hoa, Bui Thi
Phuc, Le Hong
Hien, Nguyen Quan
Vinh, Le Khanh
Tien, Nguyen Anh
Hiep, Dang Tan
Vi, Vo Thuy
Ly, Dang Ngoc
Long, Nguyen Viet
Hieu, Tran Trung
Linh, Le Viet
Minh, Nguyen Tuyet
Xuan Vuong, Bui
Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
title Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
title_full Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
title_fullStr Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
title_full_unstemmed Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
title_short Characteristics of Ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
title_sort characteristics of ag-incorporated bioactive glasses prepared by a modified sol–gel method with a shortened synthesis time and without the use of catalysts
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590098/
https://www.ncbi.nlm.nih.gov/pubmed/36329943
http://dx.doi.org/10.1039/d2ra05671b
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