Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG) is an aggressive incurable brainstem tumor that targets young children. Complete resection is not possible, and chemotherapy and radiotherapy are currently only palliative. This study aimed to identify potential therapeutic agents using a computational pipelin...

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Detalles Bibliográficos
Autores principales: Zhao, Guisheng, Newbury, Patrick, Ishi, Yukitomo, Chekalin, Eugene, Zeng, Billy, Glicksberg, Benjamin S., Wen, Anita, Paithankar, Shreya, Sasaki, Takahiro, Suri, Amreena, Nazarian, Javad, Pacold, Michael E., Brat, Daniel J., Nicolaides, Theodore, Chen, Bin, Hashizume, Rintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590174/
https://www.ncbi.nlm.nih.gov/pubmed/36274161
http://dx.doi.org/10.1186/s40478-022-01463-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590174/
https://www.ncbi.nlm.nih.gov/pubmed/36274161
http://dx.doi.org/10.1186/s40478-022-01463-z

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