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Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects
BACKGROUND: Curcumin and piperine are major bioactive compounds of Curcuma longa and Piper nigrum, widely consumed as spices and flock medicine. The combinational use of these plants is a common practice in Southeast Asia. Synergism between curcumin and piperine has been found in several animal mode...
Autores principales: | Boonrueng, Pawana, Wasana, Peththa Wadu Dasuni, Hasriadi, Vajragupta, Opa, Rojsitthisak, Pornchai, Towiwat, Pasarapa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590184/ https://www.ncbi.nlm.nih.gov/pubmed/36274168 http://dx.doi.org/10.1186/s13020-022-00660-1 |
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