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Histone deacetylase inhibitors enhance oncolytic herpes simplex virus therapy for malignant meningioma

Approximately 20% of meningiomas are not benign (higher grade) and tend to relapse after surgery and radiation therapy. Malignant (anaplastic) meningioma (MM) is a minor subset of high-grade meningioma that is lethal with no effective treatment options currently. Oncolytic herpes simplex virus (oHSV...

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Detalles Bibliográficos
Autores principales: Kawamura, Yoichiro, Hua, Lingyang, Gurtner, Alessandra, Wong, Ego, Kiyokawa, Juri, Shah, Nadia, Gorham, Joshua, Wakimoto, Hiroko, Rabkin, Samuel D., Martuza, Robert L., Wakimoto, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590235/
https://www.ncbi.nlm.nih.gov/pubmed/36271587
http://dx.doi.org/10.1016/j.biopha.2022.113843