Cargando…

Exploring molecular targets in diabetic kidney disease

Diabetic kidney disease is the leading cause of end-stage kidney disease, and it remains a major challenge. Many factors, such as glomerular hyperfiltration, oxidative stress, inflammation, hypoxia, and epigenetics, are associated with the progression of diabetic kidney disease; however, the whole m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maruno, Sayako, Tanaka, Tetsuhiro, Nangaku, Masaomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Nephrology 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590302/ https://www.ncbi.nlm.nih.gov/pubmed/35354246 http://dx.doi.org/10.23876/j.krcp.21.251

Ejemplares similares

Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease
por: Hirakawa, Yosuke, et al.
Publicado: (2017)

Treatment of Diabetic Kidney Disease: Current and Future
por: Yamazaki, Tomotaka, et al.
Publicado: (2021)

Recent advances in understanding of chronic kidney disease
por: Yamaguchi, Junna, et al.
Publicado: (2015)

Profile of Daprodustat in the Treatment of Renal Anemia Due to Chronic Kidney Disease
por: Ishii, Taisuke, et al.
Publicado: (2021)

Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes
por: Kawakami, Takahisa, et al.
Publicado: (2014)

Recent advances in renal regeneration
por: Hasegawa, Sho, et al.
Publicado: (2019)

Renal Hypoxia in CKD; Pathophysiology and Detecting Methods
por: Hirakawa, Yosuke, et al.
Publicado: (2017)

Safety and effectiveness of long-term use of darbepoetin alfa in non-dialysis patients with chronic kidney disease: a post-marketing surveillance study in Japan
por: Tanaka, Tetsuhiro, et al.
Publicado: (2018)

Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ
por: Yamaguchi, Junna, et al.
Publicado: (2015)

What’s New in the Molecular Mechanisms of Diabetic Kidney Disease: Recent Advances
por: Watanabe, Kimio, et al.
Publicado: (2022)

Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia
por: Yamazaki, Tomotaka, et al.
Publicado: (2023)

Metabolic Changes and Oxidative Stress in Diabetic Kidney Disease
por: Sakashita, Midori, et al.
Publicado: (2021)

Potential progression biomarkers of diabetic kidney disease determined using comprehensive machine learning analysis of non-targeted metabolomics
por: Hirakawa, Yosuke, et al.
Publicado: (2022)

How does diabetes cause susceptibility to COVID-19 in the kidney: new clues provided by organoids
por: Xia, Yun, et al.
Publicado: (2022)

Effect of M2-like macrophages of the injured-kidney cortex on kidney cancer progression
por: Ishii, Taisuke, et al.
Publicado: (2022)

Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan
por: Yoshida, Yui, et al.
Publicado: (2020)

Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells
por: Muratsu-Ikeda, Shiyo, et al.
Publicado: (2012)

Randomized Clinical Trial on the Effect of Bardoxolone Methyl on GFR in Diabetic Kidney Disease Patients (TSUBAKI Study)
por: Nangaku, Masaomi, et al.
Publicado: (2020)

New measures against chronic kidney diseases in Japan since 2018
por: Fukui, Akira, et al.
Publicado: (2019)

eGFR slope as a surrogate endpoint for clinical study in early stage of chronic kidney disease: from The Japan Chronic Kidney Disease Database
por: Itano, Seiji, et al.
Publicado: (2023)

The role of oxidative stress and hypoxia in renal disease
por: Honda, Tomoko, et al.
Publicado: (2019)

Persistent expression of neutrophil gelatinase‐associated lipocalin and M2 macrophage markers and chronic fibrosis after acute kidney injury
por: Saito, Hisako, et al.
Publicado: (2018)

A distinctive distribution of hypoxia‐inducible factor‐1α in cultured renal tubular cells with hypoperfusion simulated by coverslip placement
por: Honda, Tomoko, et al.
Publicado: (2020)

Summary of the 2018 ISN Frontiers Meeting: Kidney Disease and Cardiovascular Disease
por: Kume, Shinji, et al.
Publicado: (2018)

Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes
por: Mimura, Imari, et al.
Publicado: (2018)

Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner
por: Yamaguchi, Junna, et al.
Publicado: (2017)

β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice
por: Higashihara, Takaaki, et al.
Publicado: (2021)

Acetate attenuates kidney fibrosis in an oxidative stress‐dependent manner
por: Kawabata, Chiaki, et al.
Publicado: (2023)

Empagliflozin and kidney outcomes in Asian patients with type 2 diabetes and established cardiovascular disease: Results from the EMPA‐REG OUTCOME(®) trial
por: Kadowaki, Takashi, et al.
Publicado: (2019)

The Longitudinal Study of Liver Cysts in Patients With Autosomal Dominant Polycystic Kidney Disease and Polycystic Liver Disease
por: Matsuura, Ryo, et al.
Publicado: (2016)

Chromatin remodeling factor, INO80, inhibits PMAIP1 in renal tubular cells via exchange of histone variant H2A.Z. for H2A
por: Miura, Rika, et al.
Publicado: (2023)

Higher hemoglobin levels using darbepoetin alfa and kidney outcomes in advanced chronic kidney disease without diabetes: a prespecified secondary analysis of the PREDICT trial
por: Maruyama, Shoichi, et al.
Publicado: (2023)

Thyroid hormone increases oxygen metabolism causing intrarenal tissue hypoxia; a pathway to kidney disease
por: Sivertsson, Ebba, et al.
Publicado: (2022)

Novel lnc RNA regulated by HIF‐1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia
por: Mimura, Imari, et al.
Publicado: (2017)

Reduction in the magnitude of serum potassium elevation in combination therapy with esaxerenone (CS‐3150) and sodium–glucose cotransporter 2 inhibitor in patients with diabetic kidney disease: Subanalysis of two phase III studies
por: Shikata, Kenichi, et al.
Publicado: (2022)

Safety of daprodustat in patients with anemia of chronic kidney disease: A pooled analysis of phase 3 studies in Japan
por: Nangaku, Masaomi, et al.
Publicado: (2022)

Body Weight Control by a High-Carbohydrate/Low-Fat Diet Slows the Progression of Diabetic Kidney Damage in an Obese, Hypertensive, Type 2 Diabetic Rat Model
por: Ohtomo, Shuichi, et al.
Publicado: (2010)

Molecular Mechanisms of Diabetic Kidney Disease
por: Rico-Fontalvo, Jorge, et al.
Publicado: (2022)

Pathogenesis of Atypical Hemolytic Uremic Syndrome
por: Yoshida, Yoko, et al.
Publicado: (2019)

H(+)-ATPase blockade reduced renal gluconeogenesis and plasma glucose in a diabetic rat model
por: Tojo, Akihiro, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3d9ksb3td2tvse6mii4s98li57