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Peptide (Tat(48–60)) YVEEL protects against necrotizing enterocolitis through inhibition of toll-like receptor 4-mediated signaling in a phosphatidylinositol 3-kinase/AKT dependent manner

Necrotizing enterocolitis (NEC) is a catastrophic disease largely occurring in preterm infants, and toll-like receptor 4 (TLR4) has been implicated in its pathogenesis. The current therapeutic strategies for NEC are, however, far from optimal. In the present study, a whey-derived antioxidative pepti...

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Detalles Bibliográficos
Autores principales: Yan, Xiangyun, Cao, Yan, Chen, Wenjuan, Yu, Qinlei, Chen, Yanjie, Yao, Shuwen, Jiang, Chengyao, Chen, Xiaohui, Han, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590307/
https://www.ncbi.nlm.nih.gov/pubmed/36299988
http://dx.doi.org/10.3389/fnut.2022.992145