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A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022

PURPOSE: We hypothesized that SARS-CoV-2 infection numbers reported by governmental institutions are underestimated due to high dark figures as only results from polymerase chain reaction (PCR) tests are incorporated in governmental statistics and testing capacities were further restricted as of Jul...

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Autores principales: Stemler, Jannik, Salmanton-García, Jon, Weise, Ben, Többen, Christina, Joisten, Carolin, Fleig, Julian, Cornely, Oliver A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590393/
https://www.ncbi.nlm.nih.gov/pubmed/36279033
http://dx.doi.org/10.1007/s15010-022-01931-7
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author Stemler, Jannik
Salmanton-García, Jon
Weise, Ben
Többen, Christina
Joisten, Carolin
Fleig, Julian
Cornely, Oliver A.
author_facet Stemler, Jannik
Salmanton-García, Jon
Weise, Ben
Többen, Christina
Joisten, Carolin
Fleig, Julian
Cornely, Oliver A.
author_sort Stemler, Jannik
collection PubMed
description PURPOSE: We hypothesized that SARS-CoV-2 infection numbers reported by governmental institutions are underestimated due to high dark figures as only results from polymerase chain reaction (PCR) tests are incorporated in governmental statistics and testing capacities were further restricted as of July, 2022. METHODS: A point prevalence investigation was piloted by rapid antigen testing (RAT) among participants of the VACCELERATE volunteer registry. 2400 volunteers were contacted, of which 500 received a RAT including instructions for self-testing in the first week of July, 2022. Results were self-reported via e-mail. RESULTS: 419 valid RAT results were collected until July 7th, 2022. Between July-1 and July-7, 2022, 7/419 (1.67%) tests were positive. Compared to reports of the German Federal Government, our results suggest a more than twofold higher prevalence. Three out of seven positive individuals did not have a PCR test and are therefore likely not to be displayed in governmental statistics. CONCLUSION: Our findings imply that the actual prevalence of SARS-CoV-2 may be higher than detected by current surveillance systems, so that current pandemic surveillance and testing strategies may be adapted.
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spelling pubmed-95903932022-10-24 A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022 Stemler, Jannik Salmanton-García, Jon Weise, Ben Többen, Christina Joisten, Carolin Fleig, Julian Cornely, Oliver A. Infection Brief Report PURPOSE: We hypothesized that SARS-CoV-2 infection numbers reported by governmental institutions are underestimated due to high dark figures as only results from polymerase chain reaction (PCR) tests are incorporated in governmental statistics and testing capacities were further restricted as of July, 2022. METHODS: A point prevalence investigation was piloted by rapid antigen testing (RAT) among participants of the VACCELERATE volunteer registry. 2400 volunteers were contacted, of which 500 received a RAT including instructions for self-testing in the first week of July, 2022. Results were self-reported via e-mail. RESULTS: 419 valid RAT results were collected until July 7th, 2022. Between July-1 and July-7, 2022, 7/419 (1.67%) tests were positive. Compared to reports of the German Federal Government, our results suggest a more than twofold higher prevalence. Three out of seven positive individuals did not have a PCR test and are therefore likely not to be displayed in governmental statistics. CONCLUSION: Our findings imply that the actual prevalence of SARS-CoV-2 may be higher than detected by current surveillance systems, so that current pandemic surveillance and testing strategies may be adapted. Springer Berlin Heidelberg 2022-10-24 2023 /pmc/articles/PMC9590393/ /pubmed/36279033 http://dx.doi.org/10.1007/s15010-022-01931-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Report
Stemler, Jannik
Salmanton-García, Jon
Weise, Ben
Többen, Christina
Joisten, Carolin
Fleig, Julian
Cornely, Oliver A.
A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022
title A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022
title_full A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022
title_fullStr A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022
title_full_unstemmed A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022
title_short A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022
title_sort pilot surveillance report of sars-cov-2 rapid antigen test results among volunteers in germany, 1st week of july 2022
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590393/
https://www.ncbi.nlm.nih.gov/pubmed/36279033
http://dx.doi.org/10.1007/s15010-022-01931-7
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