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Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia
Having an estimate of the number of under-reported cases is crucial in determining the true burden of a disease. In the COVID-19 pandemic, there is a great need to quantify the true disease burden by capturing the true incidence rate to establish appropriate measures and strategies to combat the dis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590417/ https://www.ncbi.nlm.nih.gov/pubmed/36299511 http://dx.doi.org/10.7717/peerj.14184 |
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author | Lope, Dinah Jane Demirhan, Haydar |
author_facet | Lope, Dinah Jane Demirhan, Haydar |
author_sort | Lope, Dinah Jane |
collection | PubMed |
description | Having an estimate of the number of under-reported cases is crucial in determining the true burden of a disease. In the COVID-19 pandemic, there is a great need to quantify the true disease burden by capturing the true incidence rate to establish appropriate measures and strategies to combat the disease. This study investigates the under-reporting of COVID-19 cases in Victoria, Australia, during the third wave of the pandemic as a result of variation in geographic area and time. It is aimed to determine potential under-reported areas and generate the true picture of the disease in terms of the number of cases. A two-tiered Bayesian hierarchical model approach is employed to estimate the true incidence and detection rates through Bayesian model averaging. The proposed model goes beyond testing inequality across areas by looking into other covariates such as weather, vaccination rates, and access to vaccination and testing centres, including interactions and variations between space and time. This model aims for parsimony yet allows a broader range of scope to capture the underlying dynamic of the reported COVID-19 cases. Moreover, it is a data-driven, flexible, and generalisable model to a global context such as cross-country estimation and across time points under strict pandemic conditions. |
format | Online Article Text |
id | pubmed-9590417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95904172022-10-25 Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia Lope, Dinah Jane Demirhan, Haydar PeerJ Epidemiology Having an estimate of the number of under-reported cases is crucial in determining the true burden of a disease. In the COVID-19 pandemic, there is a great need to quantify the true disease burden by capturing the true incidence rate to establish appropriate measures and strategies to combat the disease. This study investigates the under-reporting of COVID-19 cases in Victoria, Australia, during the third wave of the pandemic as a result of variation in geographic area and time. It is aimed to determine potential under-reported areas and generate the true picture of the disease in terms of the number of cases. A two-tiered Bayesian hierarchical model approach is employed to estimate the true incidence and detection rates through Bayesian model averaging. The proposed model goes beyond testing inequality across areas by looking into other covariates such as weather, vaccination rates, and access to vaccination and testing centres, including interactions and variations between space and time. This model aims for parsimony yet allows a broader range of scope to capture the underlying dynamic of the reported COVID-19 cases. Moreover, it is a data-driven, flexible, and generalisable model to a global context such as cross-country estimation and across time points under strict pandemic conditions. PeerJ Inc. 2022-10-21 /pmc/articles/PMC9590417/ /pubmed/36299511 http://dx.doi.org/10.7717/peerj.14184 Text en ©2022 Lope and Demirhan https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Epidemiology Lope, Dinah Jane Demirhan, Haydar Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia |
title | Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia |
title_full | Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia |
title_fullStr | Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia |
title_full_unstemmed | Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia |
title_short | Spatiotemporal Bayesian estimation of the number of under-reported COVID-19 cases in Victoria Australia |
title_sort | spatiotemporal bayesian estimation of the number of under-reported covid-19 cases in victoria australia |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590417/ https://www.ncbi.nlm.nih.gov/pubmed/36299511 http://dx.doi.org/10.7717/peerj.14184 |
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