Una causa infrecuente de colestasis extrahepática: colestasis inducida por morfina

INTRODUCTION: Extrahepatic cholestasis by opiates is a very rare entity of which only case reports are recorded in the literature. METHODS: We present the case of a patient who developed abdominal pain and cholestasis after consumption of high doses of morphine for pain management of her underlying disease, treated by laparoscopic surgery. RESULTS: The patient evolved favorably in the postoperative period without bilirrhage and was discharged on the fifth day with bilirubin values within normal parameters. CONCLUSION: Sphincter of Oddi dysfunction syndrome secondary to long-term use of opioids is a very rare entity. However, it should be suspected in cases of extrahepatic cholestasis in which no stones or tumors are observed and in patients with long-term use of high-dose opiates either due to addiction or chronic pain treatment.