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HSV-1 and influenza infection induce linear and circular splicing of the long NEAT1 isoform

The herpes simplex virus 1 (HSV-1) virion host shut-off (vhs) protein cleaves both cellular and viral mRNAs by a translation-initiation-dependent mechanism, which should spare circular RNAs (circRNAs). Here, we show that vhs-mediated degradation of linear mRNAs leads to an enrichment of circRNAs rel...

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Detalles Bibliográficos
Autores principales:	Friedl, Marie-Sophie, Djakovic, Lara, Kluge, Michael, Hennig, Thomas, Whisnant, Adam W., Backes, Simone, Dölken, Lars, Friedel, Caroline C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591066/ https://www.ncbi.nlm.nih.gov/pubmed/36279270 http://dx.doi.org/10.1371/journal.pone.0276467

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