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HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system

Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus which mainly infects CD4(+) T cells and causes adult T-cell leukemia/lymphoma (ATL), is primarily transmitted via direct cell-to-cell transmission. This feature generates a wide variety of infected clones in hosts, which are maintained via cl...

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Detalles Bibliográficos
Autores principales: Tan, Benjy J. Y., Sugata, Kenji, Ono, Masahiro, Satou, Yorifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591123/
https://www.ncbi.nlm.nih.gov/pubmed/36300109
http://dx.doi.org/10.3389/fimmu.2022.991928