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Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and pathogenic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival and requires HOPS, a conserved heterohexameric tethering complex. On the membranes to be fused, HOPS binds small membrane-asso...

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Detalles Bibliográficos
Autores principales:	Shvarev, Dmitry, Schoppe, Jannis, König, Caroline, Perz, Angela, Füllbrunn, Nadia, Kiontke, Stephan, Langemeyer, Lars, Januliene, Dovile, Schnelle, Kilian, Kümmel, Daniel, Fröhlich, Florian, Moeller, Arne, Ungermann, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592082/ https://www.ncbi.nlm.nih.gov/pubmed/36098503 http://dx.doi.org/10.7554/eLife.80901

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