Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)

BACKGROUND: Aedes aegypti is the primary vector of viruses, such as Zika, chikungunya, yellow fever, and dengue. In this context, a biomonitored chemical study was conducted to evaluate the activity of the crude extract of the endophytic fungus Phomopsis sp. against the larvae of Aedes aegypti. METH...

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Autores principales: Garcia, Armando da Costa, de Menezes, Orivaldo Teixeira, Mariano, Lissa Apolonia, Santiago, Letícia Corrêa, Araújo, Ângela Regina, Monfardini, Julia Dietsche, Simões, Rejane de Castro, de Oliveira, André Correa, Roque, Rosemary Aparecida, Tadei, Wanderli Pedro, Teles, Helder Lopes, de Oliveira, Camila Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592098/
https://www.ncbi.nlm.nih.gov/pubmed/36287467
http://dx.doi.org/10.1590/0037-8682-0018-2022
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author Garcia, Armando da Costa
de Menezes, Orivaldo Teixeira
Mariano, Lissa Apolonia
Santiago, Letícia Corrêa
Araújo, Ângela Regina
Monfardini, Julia Dietsche
Simões, Rejane de Castro
de Oliveira, André Correa
Roque, Rosemary Aparecida
Tadei, Wanderli Pedro
Teles, Helder Lopes
de Oliveira, Camila Martins
author_facet Garcia, Armando da Costa
de Menezes, Orivaldo Teixeira
Mariano, Lissa Apolonia
Santiago, Letícia Corrêa
Araújo, Ângela Regina
Monfardini, Julia Dietsche
Simões, Rejane de Castro
de Oliveira, André Correa
Roque, Rosemary Aparecida
Tadei, Wanderli Pedro
Teles, Helder Lopes
de Oliveira, Camila Martins
author_sort Garcia, Armando da Costa
collection PubMed
description BACKGROUND: Aedes aegypti is the primary vector of viruses, such as Zika, chikungunya, yellow fever, and dengue. In this context, a biomonitored chemical study was conducted to evaluate the activity of the crude extract of the endophytic fungus Phomopsis sp. against the larvae of Aedes aegypti. METHODS: Crude extract, fractions, and isolated substances were evaluated in in-vitro assays against third-stage larvae of Aedes aegypti. RESULTS: We isolated 3-nitropropionic acid with an LC(50) of 15.172 ppm and LC(90) of 18.178 ppm after 24 hours of larval exposure. CONCLUSIONS: The results indicated that 3-nitropropionic acid exerted larvicidal activity.
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spelling pubmed-95920982022-11-04 Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae) Garcia, Armando da Costa de Menezes, Orivaldo Teixeira Mariano, Lissa Apolonia Santiago, Letícia Corrêa Araújo, Ângela Regina Monfardini, Julia Dietsche Simões, Rejane de Castro de Oliveira, André Correa Roque, Rosemary Aparecida Tadei, Wanderli Pedro Teles, Helder Lopes de Oliveira, Camila Martins Rev Soc Bras Med Trop Short Communication BACKGROUND: Aedes aegypti is the primary vector of viruses, such as Zika, chikungunya, yellow fever, and dengue. In this context, a biomonitored chemical study was conducted to evaluate the activity of the crude extract of the endophytic fungus Phomopsis sp. against the larvae of Aedes aegypti. METHODS: Crude extract, fractions, and isolated substances were evaluated in in-vitro assays against third-stage larvae of Aedes aegypti. RESULTS: We isolated 3-nitropropionic acid with an LC(50) of 15.172 ppm and LC(90) of 18.178 ppm after 24 hours of larval exposure. CONCLUSIONS: The results indicated that 3-nitropropionic acid exerted larvicidal activity. Sociedade Brasileira de Medicina Tropical - SBMT 2022-10-24 /pmc/articles/PMC9592098/ /pubmed/36287467 http://dx.doi.org/10.1590/0037-8682-0018-2022 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
Garcia, Armando da Costa
de Menezes, Orivaldo Teixeira
Mariano, Lissa Apolonia
Santiago, Letícia Corrêa
Araújo, Ângela Regina
Monfardini, Julia Dietsche
Simões, Rejane de Castro
de Oliveira, André Correa
Roque, Rosemary Aparecida
Tadei, Wanderli Pedro
Teles, Helder Lopes
de Oliveira, Camila Martins
Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)
title Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)
title_full Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)
title_fullStr Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)
title_full_unstemmed Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)
title_short Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)
title_sort endophytic fungus phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against aedes aegypti (linnaeus 1762, diptera: culicidae)
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592098/
https://www.ncbi.nlm.nih.gov/pubmed/36287467
http://dx.doi.org/10.1590/0037-8682-0018-2022
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