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MBTPS1 regulates proliferation of colorectal cancer primarily through its action on sterol regulatory element-binding proteins

Among the main metabolic pathways implicated in cancer cell proliferation are those of cholesterol and fatty acid synthesis, both of which are tightly regulated by sterol regulatory element-binding proteins (SREBPs). SREBPs are activated through specific cleavage by membrane-bound transcription fact...

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Detalles Bibliográficos
Autores principales: Hartal-Benishay, Liat H., Saadi, Esraa, Toubiana, Shir, Shaked, Lior, Lalzar, Maya, Abu Hatoum, Ossama, Tal, Sharon, Selig, Sara, Barki-Harrington, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592115/
https://www.ncbi.nlm.nih.gov/pubmed/36300096
http://dx.doi.org/10.3389/fonc.2022.1004014