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Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation
COVID-19 resulted in a mortality rate of 3–6% caused by SARS-CoV-2 and its variant leading to unprecedented consequences of acute respiratory distress septic shock and multiorgan failure. In such a situation, evaluation, diagnosis, treatment, and care for cancer patients are difficult tasks faced by...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592241/ https://www.ncbi.nlm.nih.gov/pubmed/36299504 http://dx.doi.org/10.1155/2022/5231022 |
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author | Bhattacharjee, Rahul Das, Debanjan Bhadhuri, Radheka Chakraborty, Srija Dey, Tanima Buragohain, Rupam Nath, Asim Muduli, Kartik Barman, Pranjan Gundamaraju, Rohit |
author_facet | Bhattacharjee, Rahul Das, Debanjan Bhadhuri, Radheka Chakraborty, Srija Dey, Tanima Buragohain, Rupam Nath, Asim Muduli, Kartik Barman, Pranjan Gundamaraju, Rohit |
author_sort | Bhattacharjee, Rahul |
collection | PubMed |
description | COVID-19 resulted in a mortality rate of 3–6% caused by SARS-CoV-2 and its variant leading to unprecedented consequences of acute respiratory distress septic shock and multiorgan failure. In such a situation, evaluation, diagnosis, treatment, and care for cancer patients are difficult tasks faced by medical staff. Moreover, patients with gynaecological cancer appear to be more prone to severe infection and mortality from COVID-19 due to immunosuppression by chemotherapy and coexisting medical disorders. To deal with such a circumtances oncologists have been obliged to reconsider the entire diagnostic, treatment, and management approach. This review will provide and discuss the molecular link with gynaecological cancer under COVID-19 infection, providing a novel bilateral relationship between the two infections. Moreover, the authors have provided insights to discuss the pathobiology of COVID-19 in gynaecological cancer and their risks associated with such comorbidity. Furthermore, we have depicted the overall impact of host immunity along with guidelines for the treatment of patients with gynaecological cancer under COVID-19 infection. We have also discussed the feasible scope for the management of COVID-19 and gynaecological cancer. |
format | Online Article Text |
id | pubmed-9592241 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-95922412022-10-25 Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation Bhattacharjee, Rahul Das, Debanjan Bhadhuri, Radheka Chakraborty, Srija Dey, Tanima Buragohain, Rupam Nath, Asim Muduli, Kartik Barman, Pranjan Gundamaraju, Rohit J Oncol Review Article COVID-19 resulted in a mortality rate of 3–6% caused by SARS-CoV-2 and its variant leading to unprecedented consequences of acute respiratory distress septic shock and multiorgan failure. In such a situation, evaluation, diagnosis, treatment, and care for cancer patients are difficult tasks faced by medical staff. Moreover, patients with gynaecological cancer appear to be more prone to severe infection and mortality from COVID-19 due to immunosuppression by chemotherapy and coexisting medical disorders. To deal with such a circumtances oncologists have been obliged to reconsider the entire diagnostic, treatment, and management approach. This review will provide and discuss the molecular link with gynaecological cancer under COVID-19 infection, providing a novel bilateral relationship between the two infections. Moreover, the authors have provided insights to discuss the pathobiology of COVID-19 in gynaecological cancer and their risks associated with such comorbidity. Furthermore, we have depicted the overall impact of host immunity along with guidelines for the treatment of patients with gynaecological cancer under COVID-19 infection. We have also discussed the feasible scope for the management of COVID-19 and gynaecological cancer. Hindawi 2022-10-17 /pmc/articles/PMC9592241/ /pubmed/36299504 http://dx.doi.org/10.1155/2022/5231022 Text en Copyright © 2022 Rahul Bhattacharjee et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Bhattacharjee, Rahul Das, Debanjan Bhadhuri, Radheka Chakraborty, Srija Dey, Tanima Buragohain, Rupam Nath, Asim Muduli, Kartik Barman, Pranjan Gundamaraju, Rohit Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation |
title | Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation |
title_full | Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation |
title_fullStr | Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation |
title_full_unstemmed | Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation |
title_short | Cellular Landscaping of COVID-19 and Gynaecological Cancers: An Infrequent Correlation |
title_sort | cellular landscaping of covid-19 and gynaecological cancers: an infrequent correlation |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592241/ https://www.ncbi.nlm.nih.gov/pubmed/36299504 http://dx.doi.org/10.1155/2022/5231022 |
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