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Risk factors associated with increased incidences of catheter-related bloodstream infection

We have implemented several preventive measures to reduce central line-associated bloodstream infection (CLABSI) in the general intensive care unit (ICU) of a university hospital in Japan. Here, we analyzed the factors associated with CLABSI in patients with central venous catheter (CVC) insertions...

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Autores principales: Moriyama, Kiyoshi, Ando, Tadao, Kotani, Mariko, Tokumine, Joho, Nakazawa, Harumasa, Motoyasu, Akira, Yorozu, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592381/
https://www.ncbi.nlm.nih.gov/pubmed/36281147
http://dx.doi.org/10.1097/MD.0000000000031160
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author Moriyama, Kiyoshi
Ando, Tadao
Kotani, Mariko
Tokumine, Joho
Nakazawa, Harumasa
Motoyasu, Akira
Yorozu, Tomoko
author_facet Moriyama, Kiyoshi
Ando, Tadao
Kotani, Mariko
Tokumine, Joho
Nakazawa, Harumasa
Motoyasu, Akira
Yorozu, Tomoko
author_sort Moriyama, Kiyoshi
collection PubMed
description We have implemented several preventive measures to reduce central line-associated bloodstream infection (CLABSI) in the general intensive care unit (ICU) of a university hospital in Japan. Here, we analyzed the factors associated with CLABSI in patients with central venous catheter (CVC) insertions and evaluated the effects of our implemented preventive measures. From July 2013 to June 2018, data was collected from the medical records of 1472 patients with 1635 CVC insertions, including age, sex, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, duration of ICU stay, duration of catheter insertion, insertion site, and mechanical ventilation status. During weekly conferences, a surveillance team comprising intensive care and infection control doctors and nurses determined the patients’ CLABSI status. The analyzed factors were compared between CLABSI and central line patients without bloodstream infection. Multivariate analysis revealed three factors associated with CLABSI. Adjusted odds ratios with 95% confidence intervals were as follows: duration of ICU stay, 1.032 (1.019–1.044); duration of catheter insertion, 1.041 (1.015–1.066); and APACHE II score, 1.051 (1.000–1.105). The prominent risk factors were associated with the severity of the initial condition and exacerbation of the clinical condition of the patients during their stays in the ICU. Further strategies to reduce CLABSI must be developed.
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spelling pubmed-95923812022-10-25 Risk factors associated with increased incidences of catheter-related bloodstream infection Moriyama, Kiyoshi Ando, Tadao Kotani, Mariko Tokumine, Joho Nakazawa, Harumasa Motoyasu, Akira Yorozu, Tomoko Medicine (Baltimore) 4900 We have implemented several preventive measures to reduce central line-associated bloodstream infection (CLABSI) in the general intensive care unit (ICU) of a university hospital in Japan. Here, we analyzed the factors associated with CLABSI in patients with central venous catheter (CVC) insertions and evaluated the effects of our implemented preventive measures. From July 2013 to June 2018, data was collected from the medical records of 1472 patients with 1635 CVC insertions, including age, sex, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, duration of ICU stay, duration of catheter insertion, insertion site, and mechanical ventilation status. During weekly conferences, a surveillance team comprising intensive care and infection control doctors and nurses determined the patients’ CLABSI status. The analyzed factors were compared between CLABSI and central line patients without bloodstream infection. Multivariate analysis revealed three factors associated with CLABSI. Adjusted odds ratios with 95% confidence intervals were as follows: duration of ICU stay, 1.032 (1.019–1.044); duration of catheter insertion, 1.041 (1.015–1.066); and APACHE II score, 1.051 (1.000–1.105). The prominent risk factors were associated with the severity of the initial condition and exacerbation of the clinical condition of the patients during their stays in the ICU. Further strategies to reduce CLABSI must be developed. Lippincott Williams & Wilkins 2022-10-21 /pmc/articles/PMC9592381/ /pubmed/36281147 http://dx.doi.org/10.1097/MD.0000000000031160 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 4900
Moriyama, Kiyoshi
Ando, Tadao
Kotani, Mariko
Tokumine, Joho
Nakazawa, Harumasa
Motoyasu, Akira
Yorozu, Tomoko
Risk factors associated with increased incidences of catheter-related bloodstream infection
title Risk factors associated with increased incidences of catheter-related bloodstream infection
title_full Risk factors associated with increased incidences of catheter-related bloodstream infection
title_fullStr Risk factors associated with increased incidences of catheter-related bloodstream infection
title_full_unstemmed Risk factors associated with increased incidences of catheter-related bloodstream infection
title_short Risk factors associated with increased incidences of catheter-related bloodstream infection
title_sort risk factors associated with increased incidences of catheter-related bloodstream infection
topic 4900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592381/
https://www.ncbi.nlm.nih.gov/pubmed/36281147
http://dx.doi.org/10.1097/MD.0000000000031160
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