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Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disease. This study aims to explore the intervention and treatment effects of aerobic exercise and different exercise modes on AD through meta-analysis. METHODS: Using the set inclusion and exclusion criteria, retrieve the China national knowledge infr...

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Autores principales: Zhou, Xin-Pei, Zhang, Li-Mei, Chen, Guo-Qiang, Wang, Shen-Wu, He, Jin-Fen, Li, Zhuang, Zhang, Ben-Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592430/
https://www.ncbi.nlm.nih.gov/pubmed/36281092
http://dx.doi.org/10.1097/MD.0000000000031177
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author Zhou, Xin-Pei
Zhang, Li-Mei
Chen, Guo-Qiang
Wang, Shen-Wu
He, Jin-Fen
Li, Zhuang
Zhang, Ben-Si
author_facet Zhou, Xin-Pei
Zhang, Li-Mei
Chen, Guo-Qiang
Wang, Shen-Wu
He, Jin-Fen
Li, Zhuang
Zhang, Ben-Si
author_sort Zhou, Xin-Pei
collection PubMed
description Alzheimer’s disease (AD) is a neurodegenerative disease. This study aims to explore the intervention and treatment effects of aerobic exercise and different exercise modes on AD through meta-analysis. METHODS: Using the set inclusion and exclusion criteria, retrieve the China national knowledge infrastructure (CNKI), Wanfang Data Knowledge Service Platform, China Science and Technology Journal Database, Cochrane Library, and PubMed were searched from January 1, 2012, to December 31, 2021. Cochrane risk bias assessment tool was used to evaluate the quality of the included articles, and ReMan5.4.1 was used for forest plot analysis of mini-mental state exam (MMSE) score indicators included in the included articles. RESULTS: Twelve randomized controlled trials and 795 samples were included. Meta analysis of all articles: I(2) = 91%, P ≤ .00001, (MD = 2.95, 95%CI [2.49, 3.40], P ≤ .00001). Meta analysis of 5 fit aerobics groups: I(2) = 4%, P = .38, (MD = 1.53, 95%CI [0.72, 2.33], P = .0002); meta-analysis of three spinning groups: I(2) = 3%, P = .36, (MD = 1.79, 95%CI [0.29, 3.29], P = .02). CONCLUSION: Aerobic exercise can effectively improve intellectual and cognitive impairment in AD patients, and for different forms of aerobic exercise, the therapeutic effect of spinning aerobic exercise is better than that of fit aerobics.
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spelling pubmed-95924302022-10-25 Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease Zhou, Xin-Pei Zhang, Li-Mei Chen, Guo-Qiang Wang, Shen-Wu He, Jin-Fen Li, Zhuang Zhang, Ben-Si Medicine (Baltimore) 3700 Alzheimer’s disease (AD) is a neurodegenerative disease. This study aims to explore the intervention and treatment effects of aerobic exercise and different exercise modes on AD through meta-analysis. METHODS: Using the set inclusion and exclusion criteria, retrieve the China national knowledge infrastructure (CNKI), Wanfang Data Knowledge Service Platform, China Science and Technology Journal Database, Cochrane Library, and PubMed were searched from January 1, 2012, to December 31, 2021. Cochrane risk bias assessment tool was used to evaluate the quality of the included articles, and ReMan5.4.1 was used for forest plot analysis of mini-mental state exam (MMSE) score indicators included in the included articles. RESULTS: Twelve randomized controlled trials and 795 samples were included. Meta analysis of all articles: I(2) = 91%, P ≤ .00001, (MD = 2.95, 95%CI [2.49, 3.40], P ≤ .00001). Meta analysis of 5 fit aerobics groups: I(2) = 4%, P = .38, (MD = 1.53, 95%CI [0.72, 2.33], P = .0002); meta-analysis of three spinning groups: I(2) = 3%, P = .36, (MD = 1.79, 95%CI [0.29, 3.29], P = .02). CONCLUSION: Aerobic exercise can effectively improve intellectual and cognitive impairment in AD patients, and for different forms of aerobic exercise, the therapeutic effect of spinning aerobic exercise is better than that of fit aerobics. Lippincott Williams & Wilkins 2022-10-21 /pmc/articles/PMC9592430/ /pubmed/36281092 http://dx.doi.org/10.1097/MD.0000000000031177 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 3700
Zhou, Xin-Pei
Zhang, Li-Mei
Chen, Guo-Qiang
Wang, Shen-Wu
He, Jin-Fen
Li, Zhuang
Zhang, Ben-Si
Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease
title Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease
title_full Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease
title_fullStr Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease
title_full_unstemmed Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease
title_short Meta analysis of aerobic exercise improving intelligence and cognitive function in patients with Alzheimer’s disease
title_sort meta analysis of aerobic exercise improving intelligence and cognitive function in patients with alzheimer’s disease
topic 3700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592430/
https://www.ncbi.nlm.nih.gov/pubmed/36281092
http://dx.doi.org/10.1097/MD.0000000000031177
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