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Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes
Herein, we investigated the electrochemical behaviour of fMWCNTs decorated with Co-Nd bimetallic nanoparticles and alumina nanoparticles (Co-Nd/Al(2)O(3)@fMWCNTs). The nanocomposites were synthesised using simple mechanical mixing and characterised by FT-IR, XRD, UV–visible studies, SEM, TEM and EDA...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592539/ https://www.ncbi.nlm.nih.gov/pubmed/36280636 http://dx.doi.org/10.1007/s11356-022-23660-y |
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author | Agrahari, Shreanshi Singh, Ankit Kumar Gautam, Ravindra Kumar Tiwari, Ida |
author_facet | Agrahari, Shreanshi Singh, Ankit Kumar Gautam, Ravindra Kumar Tiwari, Ida |
author_sort | Agrahari, Shreanshi |
collection | PubMed |
description | Herein, we investigated the electrochemical behaviour of fMWCNTs decorated with Co-Nd bimetallic nanoparticles and alumina nanoparticles (Co-Nd/Al(2)O(3)@fMWCNTs). The nanocomposites were synthesised using simple mechanical mixing and characterised by FT-IR, XRD, UV–visible studies, SEM, TEM and EDAX. Moreover, the crystalline size of the synthesised nanoparticles was also calculated using XRD data (Debye–Scherer formula) and was found in the nm range. The electrochemical behaviour of epinephrine (EP) was examined in the presence of Co-Nd/Al(2)O(3)@fMWCNTs nanocomposite modified glassy carbon electrode (GCE) using various electrochemical techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), electrochemical impedance spectroscopy (EIS), and chronocoulometry. Among all the above-mentioned techniques, the DPV response of the modified Co-Nd/Al(2)O(3)@fMWCNTs/GCE under optimal circumstances revealed a dual linear range (0.2 to 4000 µM and 4000 to 14,000 µM) and LOD of 0.015 µM (S/N = 3). The sensitivities were determined to be 0.00323 µAµM(−1) and 0.0004 µAµM(−1) in 0.2 to 4000 µM and 4000 to 14,000 µM concentration ranges. Using chronocoulometry, the surface coverage of Co-Nd/Al(2)O(3)@fMWCNTs/GCE was calculated to be 1.37 × 10(−8) mol cm(−2). The fabricated Co-Nd/Al(2)O(3)@fMWCNTs/GCE demonstrated remarkable repeatability, with an RSD of 0.09%, and storage stability of 3 weeks, with 89.6% current retention. Lastly, it was found that Co-Nd/Al(2)O(3)@fMWCNTs/GCE worked well for EP analysis in a variety of biological fluids. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-9592539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-95925392022-10-25 Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes Agrahari, Shreanshi Singh, Ankit Kumar Gautam, Ravindra Kumar Tiwari, Ida Environ Sci Pollut Res Int Carbon-based Nanomaterials: Systematic Enumeration and Proficient Template for Detection and Remediation of Hazardous Pollutants Herein, we investigated the electrochemical behaviour of fMWCNTs decorated with Co-Nd bimetallic nanoparticles and alumina nanoparticles (Co-Nd/Al(2)O(3)@fMWCNTs). The nanocomposites were synthesised using simple mechanical mixing and characterised by FT-IR, XRD, UV–visible studies, SEM, TEM and EDAX. Moreover, the crystalline size of the synthesised nanoparticles was also calculated using XRD data (Debye–Scherer formula) and was found in the nm range. The electrochemical behaviour of epinephrine (EP) was examined in the presence of Co-Nd/Al(2)O(3)@fMWCNTs nanocomposite modified glassy carbon electrode (GCE) using various electrochemical techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), electrochemical impedance spectroscopy (EIS), and chronocoulometry. Among all the above-mentioned techniques, the DPV response of the modified Co-Nd/Al(2)O(3)@fMWCNTs/GCE under optimal circumstances revealed a dual linear range (0.2 to 4000 µM and 4000 to 14,000 µM) and LOD of 0.015 µM (S/N = 3). The sensitivities were determined to be 0.00323 µAµM(−1) and 0.0004 µAµM(−1) in 0.2 to 4000 µM and 4000 to 14,000 µM concentration ranges. Using chronocoulometry, the surface coverage of Co-Nd/Al(2)O(3)@fMWCNTs/GCE was calculated to be 1.37 × 10(−8) mol cm(−2). The fabricated Co-Nd/Al(2)O(3)@fMWCNTs/GCE demonstrated remarkable repeatability, with an RSD of 0.09%, and storage stability of 3 weeks, with 89.6% current retention. Lastly, it was found that Co-Nd/Al(2)O(3)@fMWCNTs/GCE worked well for EP analysis in a variety of biological fluids. GRAPHICAL ABSTRACT: [Image: see text] Springer Berlin Heidelberg 2022-10-25 /pmc/articles/PMC9592539/ /pubmed/36280636 http://dx.doi.org/10.1007/s11356-022-23660-y Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Carbon-based Nanomaterials: Systematic Enumeration and Proficient Template for Detection and Remediation of Hazardous Pollutants Agrahari, Shreanshi Singh, Ankit Kumar Gautam, Ravindra Kumar Tiwari, Ida Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
title | Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
title_full | Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
title_fullStr | Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
title_full_unstemmed | Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
title_short | Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
title_sort | voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from co-nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes |
topic | Carbon-based Nanomaterials: Systematic Enumeration and Proficient Template for Detection and Remediation of Hazardous Pollutants |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592539/ https://www.ncbi.nlm.nih.gov/pubmed/36280636 http://dx.doi.org/10.1007/s11356-022-23660-y |
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