Heterologously secreted MbxA from Moraxella bovis induces a membrane blebbing response of the human host cell

Many proteins of the Repeats in Toxins (RTX) protein family are toxins of Gram-negative pathogens including hemolysin A (HlyA) of uropathogenic E. coli. RTX proteins are secreted via Type I secretion systems (T1SS) and adopt their native conformation in the Ca(2+)-rich extracellular environment. Her...

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Detalles Bibliográficos
Autores principales: Erenburg, Isabelle N., Hänsch, Sebastian, Chacko, Feby M., Hamacher, Anna, Wintgens, Sebastian, Stuhldreier, Fabian, Poschmann, Gereon, Spitz, Olivia, Stühler, Kai, Wesselborg, Sebastian, Hegemann, Johannes H., Smits, Sander H. J., Weidtkamp-Peters, Stefanie, Schmitt, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592583/
https://www.ncbi.nlm.nih.gov/pubmed/36280777
http://dx.doi.org/10.1038/s41598-022-22480-x

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