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Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune response
Pore-forming Gasdermin protein-induced pyroptosis in tumor cells promotes anti-tumor immune response through the release of pro-inflammatory cytokines and immunogenic substances after cell rupture. However, endosomal sorting complexes required for transport (ESCRT) III-mediated cell membrane repair...
Autores principales: | Li, Zhaoting, Mo, Fanyi, Wang, Yixin, Li, Wen, Chen, Yu, Liu, Jun, Chen-Mayfield, Ting-Jing, Hu, Quanyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592600/ https://www.ncbi.nlm.nih.gov/pubmed/36280674 http://dx.doi.org/10.1038/s41467-022-34036-8 |
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