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Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune response

Pore-forming Gasdermin protein-induced pyroptosis in tumor cells promotes anti-tumor immune response through the release of pro-inflammatory cytokines and immunogenic substances after cell rupture. However, endosomal sorting complexes required for transport (ESCRT) III-mediated cell membrane repair...

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Detalles Bibliográficos
Autores principales: Li, Zhaoting, Mo, Fanyi, Wang, Yixin, Li, Wen, Chen, Yu, Liu, Jun, Chen-Mayfield, Ting-Jing, Hu, Quanyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592600/
https://www.ncbi.nlm.nih.gov/pubmed/36280674
http://dx.doi.org/10.1038/s41467-022-34036-8

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