Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis

BACKGROUND: Recent evidence has indicated that alterations in energy metabolism play a critical role in the pathogenesis of fibrotic diseases. Studies have suggested that ‘metabolic reprogramming’ involving the glycolysis and oxidative phosphorylation (OXPHOS) in cells lead to an enhanced generation...

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Detalles Bibliográficos
Autores principales: Cantanhede, Isabella Gomes, Liu, Huan, Balbuena Rodriguez, Vestaen, Shiwen, Xu, Ong, Voo H., Denton, Christopher P., Ponticos, Markella, Xiong, Guo, Lima-Filho, José Luiz, Abraham, David, Abu-Hanna, Jeries, Taanman, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592691/
https://www.ncbi.nlm.nih.gov/pubmed/36304460
http://dx.doi.org/10.3389/fimmu.2022.1004949

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