The status of industrialization and development of exosomes as a drug delivery system: A review

Exosomes, as natural biomolecular carriers produced by cells, have the potential and advantage of delivering drugs to target organs or cells in vivo. The steps to improve exosomes as a drug delivery system can be divided into three steps:large-scale preparation of exosomes, loading of drugs and targ...

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Autores principales: Yin, Yi, Han, Xing, Li, Cheng, Sun, Tonghui, Li, Kailin, Liu, Xionghao, Liu, Mujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592696/
https://www.ncbi.nlm.nih.gov/pubmed/36304147
http://dx.doi.org/10.3389/fphar.2022.961127
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author Yin, Yi
Han, Xing
Li, Cheng
Sun, Tonghui
Li, Kailin
Liu, Xionghao
Liu, Mujun
author_facet Yin, Yi
Han, Xing
Li, Cheng
Sun, Tonghui
Li, Kailin
Liu, Xionghao
Liu, Mujun
author_sort Yin, Yi
collection PubMed
description Exosomes, as natural biomolecular carriers produced by cells, have the potential and advantage of delivering drugs to target organs or cells in vivo. The steps to improve exosomes as a drug delivery system can be divided into three steps:large-scale preparation of exosomes, loading of drugs and targeted delivery of exosomes. Based on the existing production process and technology, there is still much room for improvement. This review highlights the research progress in three aspects and proposes new technologies and innovative approaches to improve the efficiency of exosome delivery.
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spelling pubmed-95926962022-10-26 The status of industrialization and development of exosomes as a drug delivery system: A review Yin, Yi Han, Xing Li, Cheng Sun, Tonghui Li, Kailin Liu, Xionghao Liu, Mujun Front Pharmacol Pharmacology Exosomes, as natural biomolecular carriers produced by cells, have the potential and advantage of delivering drugs to target organs or cells in vivo. The steps to improve exosomes as a drug delivery system can be divided into three steps:large-scale preparation of exosomes, loading of drugs and targeted delivery of exosomes. Based on the existing production process and technology, there is still much room for improvement. This review highlights the research progress in three aspects and proposes new technologies and innovative approaches to improve the efficiency of exosome delivery. Frontiers Media S.A. 2022-10-11 /pmc/articles/PMC9592696/ /pubmed/36304147 http://dx.doi.org/10.3389/fphar.2022.961127 Text en Copyright © 2022 Yin, Han, Li, Sun, Li, Liu and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Yin, Yi
Han, Xing
Li, Cheng
Sun, Tonghui
Li, Kailin
Liu, Xionghao
Liu, Mujun
The status of industrialization and development of exosomes as a drug delivery system: A review
title The status of industrialization and development of exosomes as a drug delivery system: A review
title_full The status of industrialization and development of exosomes as a drug delivery system: A review
title_fullStr The status of industrialization and development of exosomes as a drug delivery system: A review
title_full_unstemmed The status of industrialization and development of exosomes as a drug delivery system: A review
title_short The status of industrialization and development of exosomes as a drug delivery system: A review
title_sort status of industrialization and development of exosomes as a drug delivery system: a review
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592696/
https://www.ncbi.nlm.nih.gov/pubmed/36304147
http://dx.doi.org/10.3389/fphar.2022.961127
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