Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein

A study recently published in hepatology communications provided insights into a variant of MTARC1 protein, which conveys protection against liver disease. Here, we report a crystal structure of the variant protein at near‐atomic resolution and compare it to the structure of the wildtype protein.[Im...

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Detalles Bibliográficos
Autores principales: Struwe, Michel A., Clement, Bernd, Scheidig, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592780/
https://www.ncbi.nlm.nih.gov/pubmed/35560545
http://dx.doi.org/10.1002/hep4.1984
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author Struwe, Michel A.
Clement, Bernd
Scheidig, Axel
author_facet Struwe, Michel A.
Clement, Bernd
Scheidig, Axel
author_sort Struwe, Michel A.
collection PubMed
description A study recently published in hepatology communications provided insights into a variant of MTARC1 protein, which conveys protection against liver disease. Here, we report a crystal structure of the variant protein at near‐atomic resolution and compare it to the structure of the wildtype protein.[Image: see text]
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spelling pubmed-95927802022-10-26 Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein Struwe, Michel A. Clement, Bernd Scheidig, Axel Hepatol Commun Correspondence A study recently published in hepatology communications provided insights into a variant of MTARC1 protein, which conveys protection against liver disease. Here, we report a crystal structure of the variant protein at near‐atomic resolution and compare it to the structure of the wildtype protein.[Image: see text] John Wiley and Sons Inc. 2022-05-13 /pmc/articles/PMC9592780/ /pubmed/35560545 http://dx.doi.org/10.1002/hep4.1984 Text en © 2022 The Authors. Hepatology Communications published by Wiley Periodicals LLC on behalf of American Association for the Study of Liver Diseases. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Correspondence
Struwe, Michel A.
Clement, Bernd
Scheidig, Axel
Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein
title Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein
title_full Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein
title_fullStr Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein
title_full_unstemmed Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein
title_short Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein
title_sort letter to the editor: the clinically relevant mtarc1 p.ala165thr variant impacts neither the fold nor active site architecture of the human marc1 protein
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592780/
https://www.ncbi.nlm.nih.gov/pubmed/35560545
http://dx.doi.org/10.1002/hep4.1984
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