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Population‐based meta‐analysis and gene‐set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids

Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide. NAFLD is associated with elevated serum triglycerides (TG), low‐density lipoprotein cholesterol (LDL), and reduced high‐density lipoprotein cholesterol (HDL). Both NAFLD and blood lipid levels are genetically influenced and may share a...

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Detalles Bibliográficos
Autores principales: Handelman, Samuel K., Puentes, Yindra M., Kuppa, Annapurna, Chen, Yanhua, Du, Xiaomeng, Feitosa, Mary F., Palmer, Nicholette D., Speliotes, Elizabeth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592792/
https://www.ncbi.nlm.nih.gov/pubmed/36098472
http://dx.doi.org/10.1002/hep4.2066