A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish

Hepatic cysts are fluid‐filled lesions in the liver that are estimated to occur in 5% of the population. They may cause hepatomegaly and abdominal pain. Progression to secondary fibrosis, cirrhosis, or cholangiocarcinoma can lead to morbidity and mortality. Previous studies of patients and rodent mo...

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Detalles Bibliográficos
Autores principales: Ellis, Jillian L., Evason, Kimberley J., Zhang, Changwen, Fourman, Makenzie N., Liu, Jiandong, Ninov, Nikolay, Delous, Marion, Vanhollebeke, Benoit, Fiddes, Ian, Otis, Jessica P., Houvras, Yariv, Farber, Steven A., Xu, Xiaolei, Lin, Xueying, Stainier, Didier Y. R., Yin, Chunyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592797/
https://www.ncbi.nlm.nih.gov/pubmed/36017776
http://dx.doi.org/10.1002/hep4.2038

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