MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma

Objectives: .Asthma is a highly heterogeneous disease, and T-helper cell type 17 (Th17) cells play a pathogenic role in the development of non-T2 severe asthma. Misshapen like kinase 1 (MINK1) is involved in the regulation of Th17 cell differentiation, but its effect on severe asthma remains unclear...

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Detalles Bibliográficos
Autores principales: Chen, Zhifeng, Shang, Yulin, Yuan, Yu, He, Yi, Wasti, Binaya, Duan, Wentao, Ouyang, Ruoyun, Jia, Jingsi, Xiao, Bing, Zhang, Dongshan, Zhang, Xiufeng, Li, Jianmin, Chen, Bolin, Liu, Yi, Zeng, Qingping, Ji, Xiaoying, Ma, Libing, Liu, Shaokun, Xiang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592806/
https://www.ncbi.nlm.nih.gov/pubmed/36303542
http://dx.doi.org/10.3389/fgene.2022.959059

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