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A multi-task FP-GNN framework enables accurate prediction of selective PARP inhibitors

PARP (poly ADP-ribose polymerase) family is a crucial DNA repair enzyme that responds to DNA damage, regulates apoptosis, and maintains genome stability; therefore, PARP inhibitors represent a promising therapeutic strategy for the treatment of various human diseases including COVID-19. In this stud...

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Detalles Bibliográficos
Autores principales:	Ai, Daiqiao, Wu, Jingxing, Cai, Hanxuan, Zhao, Duancheng, Chen, Yihao, Wei, Jiajia, Xu, Jianrong, Zhang, Jiquan, Wang, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592829/ https://www.ncbi.nlm.nih.gov/pubmed/36304149 http://dx.doi.org/10.3389/fphar.2022.971369

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