Disturbance of the Warburg effect by dichloroacetate and niclosamide suppresses the growth of different sub-types of malignant pleural mesothelioma in vitro and in vivo

Background: Inhalation of asbestos fibers is the most common cause of malignant pleural mesothelioma (MPM). In 2004, the United States Food and Drug Administration approved a combination of cisplatin with pemetrexed to treat unresectable MPM. Nonetheless novel treatment is urgently needed. The objec...

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Detalles Bibliográficos
Autores principales: Lam, Sze-Kwan, Yan, Sheng, Lam, Joyce Sze-Man, Feng, Yuqian, Khan, Mahjabin, Chen, Caoyang, Ko, Frankie Chi-Fat, Ho, James Chung-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592830/
https://www.ncbi.nlm.nih.gov/pubmed/36304150
http://dx.doi.org/10.3389/fphar.2022.1020343

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